Dilution Information
Rabbit SOX-2 Monoclonal Antibody | anti-SOX-2 antibody
SOX-2 (RM427)
Reactivity
Human, Predicted: Mouse
Synonyms
SOX-2; Monoclonal Antibody; SOX-2 (RM427); Sox2; anti-sox-2; anti-sox2; sox 2; sox-2; anti sox-2; Sox 2;anti Sox 2; anti Sox-2; anti Sox2; anti SRY-related HMG-box transcription factor 2; anti-Sox 2; anti-Sox-2; anti-Sox2; anti-SRY-related HMG-box transcription factor 2; SRY-related HMG-box transcription factor 2; ANOP3; MCOPS3; MGC2413; SRY sex determining region Y box 2; SRY related HMG box gene 2; transcription factor SOX 2; transcription factor SOX2; anti-SOX-2 antibody
Host
Rabbit
Reactivity
Human, Predicted: Mouse
Clonality
Monoclonal
Isotype
IgG
Clone Number
RM427
Form/Format
Paraffin, Frozen
Anti-SOX-2 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH7.5, containing BSA and sodium azide as a preservative.
Anti-SOX-2 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH7.5, containing BSA and sodium azide as a preservative.
Immunogen
A peptide corresponding to the C-terminus of human SOX2
Control
Brain, Oligodendroglioma, Squamous Cell Carcinoma
Localization
Nuclear
Preparation and Storage
Store at 2-8 degree C (Control Slides: Store at 20-25 degree C)
Dilution Information
Dilution Information
Immunohistochemistry (IHC)
(SOX-2 Antibody Immunohistochemistry on an FFPE Brain Tissue)
Immunohistochemistry (IHC)
(SOX-2 Antibody Immunohistochemistry on an FFPE Brain Tissue)
Related Product Information for anti-SOX-2 antibody
SRY (sex determining region Y)-box 2, also known as SOX-2, is a transcription factor that is essential for maintaining self-renewal, or pluripotency, of undifferentiated embryonic stem cells. It is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach.
SOX-2 antibody is expressed in fetal brain and is used as a marker for multipotential neural stem cells. In tumors, SOX-2 expression is observed in teratoma of the central nervous system, melanoma, testicular germ cell tumor, cervical carcinoma, lung cancer, breast cancer with basal cell phenotype, and squamous cell carcinoma of the gastrointestinal tract. SOX-2 may be useful in the identification of embryonal carcinoma. In stage I lung adenocarcinomas, SOX2 seems to be an independent predictor of poor outcome and may help stratify patients at increased risk for recurrence.
SOX-2 antibody is expressed in fetal brain and is used as a marker for multipotential neural stem cells. In tumors, SOX-2 expression is observed in teratoma of the central nervous system, melanoma, testicular germ cell tumor, cervical carcinoma, lung cancer, breast cancer with basal cell phenotype, and squamous cell carcinoma of the gastrointestinal tract. SOX-2 may be useful in the identification of embryonal carcinoma. In stage I lung adenocarcinomas, SOX2 seems to be an independent predictor of poor outcome and may help stratify patients at increased risk for recurrence.
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Product Notes
The SOX-2 (Catalog #AAA370535) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SOX-2 (RM427) reacts with Human, Predicted: Mouse and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "SOX-2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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