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Western Blot (WB) ()

Mouse PP2A alpha/beta Monoclonal Antibody | anti-PP2A alpha/beta antibody

PP2A alpha/beta antibody

Gene Names
ppp2r2a; pp2a
Applications
Western Blot, Immunoprecipitation
Purity
PP2A alpha/beta antibody was purified by ammonium sulfate precipitation
Synonyms
PP2A alpha/beta; Monoclonal Antibody; PP2A alpha/beta antibody; Monoclonal PP2A alpha/beta; Anti-PP2A alpha/beta; PPP2CA; protein phosphatase 2; catalytic subunit; alpha isozyme; BOS_8121; PP2A; Pp2a1; PP2A-alpha; PP2Ac; PP2CA; PP2Calpha; protein phosphatase-2A-alpha; protein phosphatase 2A alpha subunit; protein phosphatase 2a; alpha isoform; protein phosphatase 2A catalytic subunit; protein phosphatase 2A; beta isoform; protein phosphatase 2 (formerly 2A); R75353; RCJMB04_3c21; replication protein C; RP23-46N3.2; rp-c; serine/threonine protein phosphatase 2A; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; type 2A protein phosphatase catalytic subunit; anti-PP2A alpha/beta antibody
Ordering
Host
Mouse
Clonality
Monoclonal
Isotype
IgG2b kappa
Clone Number
20G6
Purity/Purification
PP2A alpha/beta antibody was purified by ammonium sulfate precipitation
Form/Format
Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol
Sequence Length
444
Applicable Applications for anti-PP2A alpha/beta antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes
WB: 1:2000
IP: 3 ul
Biological Significance
PP2A comprises A and B subunits which are regulatory and a catalytic C subunit. When the PP2A catalytic C subunit (36 kDa) associates with the regulatory A (65 kDa, PR65) and B subunits (PR55, PR56, PR72, PR93 etc), wide variety of heterotrimeric holoenzymes are produced with distinct functions and characteristics. The different association of the subunits give PP2A large regulatory flexibility and differential substrate specificity. The A subunit exists as two isoforms (alpha and beta) as does the C subunit, whereas the B subunits fall into three families designated B, B' (also called B56), and B''. The A subunit is the scaffold required for the formation of the heterotrimeric complex and the binding of A subunit alters the enzymatic activity of the catalytic subunit, even if the B subunit is absent.
Cross-Reactivity
Human, Mouse, Rat
Immunogen
PP2A alpha/beta antibody was raised in Mouse using a synthetic target peptide as the immunogen
Preparation and Storage
Aliquot and store for 1 year at -20 degree C, avoid freeze/thaw cycles

Western Blot (WB)

()

Western Blot (WB) ()
Related Product Information for anti-PP2A alpha/beta antibody
Mouse monoclonal PP2A alpha/beta antibody
Product Categories/Family for anti-PP2A alpha/beta antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
protein phosphatase 2, regulatory subunit B, alpha
NCBI Official Synonym Full Names
protein phosphatase 2, regulatory subunit B, alpha<
NCBI Official Symbol
ppp2r2a
NCBI Official Synonym Symbols
pp2a
NCBI Protein Information
protein phosphatase 2, regulatory subunit B, alpha

Research Articles on PP2A alpha/beta

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Product Notes

The PP2A alpha/beta (Catalog #AAA833327) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PP2A alpha/beta can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP). WB: 1:2000 IP: 3 ul. Researchers should empirically determine the suitability of the PP2A alpha/beta for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PP2A alpha/beta, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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