Rabbit anti-Mouse PIGR Monoclonal Antibody | anti-PIGR antibody
Recombinant Anti-PIGR Antibody, Rabbit Monoclonal
Reactivity
Mouse
Applications
ELISA, ELISA
Purity
Protein A
Synonyms
PIGR; Monoclonal Antibody; Recombinant Anti-PIGR Antibody; Rabbit Monoclonal; PIGR/Poly-Ig Receptor Antibody; Rabbit MAb; polymeric immunoglobulin receptor; Anti-Pigr Antibody; anti-PIGR antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone Number
40
Specificity
Mouse PIGR/Poly-Ig Receptor
Purity/Purification
Protein A
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-PIGR antibody
ELISA (EIA), ELISA (EIA) (Cap)
Application Notes
ELISA: 1:5000-1:10,000
ELISA (Cap): 1:250-1:2000
ELISA (Cap): This antibody will detect Mouse PIGR in ELISA pair set.
In a sandwich ELISA, it can be used as capture antibody.
ELISA (Cap): 1:250-1:2000
ELISA (Cap): This antibody will detect Mouse PIGR in ELISA pair set.
In a sandwich ELISA, it can be used as capture antibody.
Antibody Type
Recombinant Antibody
Immunogen
Recombinant Mouse PIGR protein
Conjugation
Unconjugated
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse PIGR extracellular domain (rM PIGR).
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Related Product Information for anti-PIGR antibody
Polymeric immunoglobulin receptor, also known as PIGR, is a member of the immunoglobulin superfamily and a Fc receptor. The ectodomain of this receptor consists of five units with homology to the variable units of immunoglobulins and a transmembrane region, which also has some homology to certain immunoglobulin variable regions. PIGR is expressed on several glandular epithelia including those of liver and breast. The deduced amino-acid sequence has a length of 764 residues and shows an overall similarity of 56% and 64% with the rabbit and rat counterpart. PIGR mediates transcellular transport of polymeric immunoglobulin molecules, and thus facilitates the secretion of IgA and IgM. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment of PIGR.
References
Coyne, R. S. et al., 1995, J. Biol. Chem. 269 (50) :31620-31625. Kaetzel, C.S., 2001, Curr Biol. 11(1): R35-38.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
84,999 Da
NCBI Official Full Name
polymeric immunoglobulin receptor
NCBI Official Synonym Full Names
polymeric immunoglobulin receptor
NCBI Official Symbol
Pigr
NCBI Protein Information
polymeric immunoglobulin receptor
UniProt Protein Name
Polymeric immunoglobulin receptor
Protein Family
UniProt Gene Name
Pigr
UniProt Synonym Gene Names
PIgR; Poly-Ig receptor
Uniprot Description
This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment ().
Research Articles on PIGR
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Product Notes
The PIGR pigr (Catalog #AAA8111013) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Anti-PIGR Antibody, Rabbit Monoclonal reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PIGR can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), ELISA (EIA) (Cap). ELISA: 1:5000-1:10,000 ELISA (Cap): 1:250-1:2000 ELISA (Cap): This antibody will detect Mouse PIGR in ELISA pair set. In a sandwich ELISA, it can be used as capture antibody. Researchers should empirically determine the suitability of the PIGR pigr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PIGR, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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