Western Blot (WB)
(Western blot analysis of PGRP-1a in cell lysates from human brain using MBS600020 at a dilution of 1:500.)
Mouse anti-Human PGRP-1a Monoclonal Antibody
PGRP-1a (Peptidoglycan Recognition Protein-1a)
Reactivity
Human
Applications
ELISA, Western Blot, Immunocytochemistry, Flow Cytometry, Functional Assay
Purity
AscitesAscites
Synonyms
PGRP-1a; Monoclonal Antibody; PGRP-1a (Peptidoglycan Recognition Protein-1a); Anti -PGRP-1a (Peptidoglycan Recognition Protein-1a); anti-PGRP-1a antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
6D651
Specificity
Recognizes human PGRP-1a.
Purity/Purification
Ascites
Ascites
Ascites
Form/Format
Supplied as a liquid, 0.05% sodium azide
Applicable Applications for anti-PGRP-1a antibody
ELISA (EL/EIA), Western Blot (WB), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS)
Application Notes
Suitable for use in Flow Cytometry, ELISA, Western Blot and Immunocytochemistry.
Dilution: Western Blot: 1:500-1:1000
Dilution: Western Blot: 1:500-1:1000
Immunogen
Synthetic peptide corresponding to aa178-193 of human PGRP-1a (peptidoglycan recognition protein-1a).
Positive Control
Whole cell lysate from human brain cells
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western blot analysis of PGRP-1a in cell lysates from human brain using MBS600020 at a dilution of 1:500.)
Western Blot (WB)
(Western blot analysis of PGRP-1a in cell lysates from human brain using MBS600020 at a dilution of 1:500.)
Related Product Information for anti-PGRP-1a antibody
Primary immune recognition is based on structures common among invading pathogens. Bacterial surface molecules, such as lipopolysaccharide (LPS) and peptidoglycan (PGN), are known to elicit immune reactions ranging from cytokine release to fever. Recently, a family of proteins called peptidoglycan recognition protein (PGRP) has been identified in mouse and human that binds to peptidoglycans expressed on Gram-positive bacteria. Peptidoglycan (PGN) is an essential cell wall component of virtually all bacteria and, thus, it is an excellent target for recognition by the eukaryotic innate immune system. The PGRPs (PGRP-L, PGRP-S, PGRP-Ia, and PGRP-Ib) define a new family of human pattern recognition molecules. PGRP-L is primarily expressed in the liver. Although liver is not considered a primary immune organ, liver participates in host defenses by producing acute phase proteins (by hepatocytes) in response to infections and by clearing microorganisms from blood. PGRP-1a mRNA is highly expressed in esophagus, tonsils and thymus and to lesser extent in the stomach, rectum, and brain.
Product Categories/Family for anti-PGRP-1a antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI Official Full Name
peptidoglycan recognition protein 1A
Similar Products
Product Notes
The PGRP-1a (Catalog #AAA600020) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PGRP-1a (Peptidoglycan Recognition Protein-1a) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PGRP-1a can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS). Suitable for use in Flow Cytometry, ELISA, Western Blot and Immunocytochemistry. Dilution: Western Blot: 1:500-1:1000. Researchers should empirically determine the suitability of the PGRP-1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PGRP-1a, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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