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Western Blot (WB) (Western blot analysis of lysates from mouse brain, rat brain tissue lysate (from left to right), using Ntrk3 Antibody. MBS9200051 was diluted at 1:1000 at each lane. A goat anti-mouse IgG H&L(HRP) at 1:3000 dilution was used as the secondary antibody. Lysates at 20ug per lane.)

Mouse Ntrk3 Monoclonal Antibody | anti-Ntrk3 antibody

Ntrk3 Antibody

Gene Names
Ntrk3; TrkC; AW125844; Ntrk3_tv3
Reactivity
Human, mouse, rat
Applications
Western Blot, ELISA
Purity
Purified Mouse Monoclonal Antibody (Mab)
Synonyms
Ntrk3; Monoclonal Antibody; Ntrk3 Antibody; NT-3 growth factor receptor; GP145-TrkC; Trk-C; Neurotrophic tyrosine kinase receptor type 3; TrkC tyrosine kinase; TrkC; anti-Ntrk3 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human, mouse, rat
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
1454CT394.87.35
Specificity
This Ntrk3 antibody is generated from a mouse immunized with a recombinant protein of human Ntrk3.
Purity/Purification
Purified Mouse Monoclonal Antibody (Mab)
Form/Format
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Sequence Length
612
Applicable Applications for anti-Ntrk3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Crown Antibody
Yes
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Western blot analysis of lysates from mouse brain, rat brain tissue lysate (from left to right), using Ntrk3 Antibody. MBS9200051 was diluted at 1:1000 at each lane. A goat anti-mouse IgG H&L(HRP) at 1:3000 dilution was used as the secondary antibody. Lysates at 20ug per lane.)

Western Blot (WB) (Western blot analysis of lysates from mouse brain, rat brain tissue lysate (from left to right), using Ntrk3 Antibody. MBS9200051 was diluted at 1:1000 at each lane. A goat anti-mouse IgG H&L(HRP) at 1:3000 dilution was used as the secondary antibody. Lysates at 20ug per lane.)

Western Blot (WB)

(Western blot analysis of lysate from human brain tissue lysate, using Ntrk3 Antibody. MBS9200051 was diluted at 1:1000. A goat anti-mouse IgG H&L(HRP) at 1:3000 dilution was used as the secondary antibody. Lysate at 20ug.)

Western Blot (WB) (Western blot analysis of lysate from human brain tissue lysate, using Ntrk3 Antibody. MBS9200051 was diluted at 1:1000. A goat anti-mouse IgG H&L(HRP) at 1:3000 dilution was used as the secondary antibody. Lysate at 20ug.)
Related Product Information for anti-Ntrk3 antibody
Receptor for neurotrophin-3 (NT-3). This is a tyrosine- protein kinase receptor. Known substrates for the Trk receptors are SHC1, PI 3-kinase, and PLC-gamma-1 (By similarity).
Product Categories/Family for anti-Ntrk3 antibody
References
Yamauchi J.,et al.Proc. Natl. Acad. Sci. U.S.A. 100:14421-14426(2003).
Menn B.,et al.J. Comp. Neurol. 401:47-64(1998).
Ballif B.A.,et al.J. Proteome Res. 7:311-318(2008).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
92760
NCBI Official Full Name
NT-3 growth factor receptor isoform a
NCBI Official Synonym Full Names
neurotrophic tyrosine kinase, receptor, type 3
NCBI Official Symbol
Ntrk3
NCBI Official Synonym Symbols
TrkC; AW125844; Ntrk3_tv3
NCBI Protein Information
NT-3 growth factor receptor
UniProt Protein Name
NT-3 growth factor receptor
UniProt Gene Name
Ntrk3
UniProt Synonym Gene Names
TrkC; Trk-C
UniProt Entry Name
NTRK3_MOUSE

Uniprot Description

TrkC: a receptor tyrosine kinase of the TRK family. Receptor for neurotrophin-3 (NT-3). Known substrates for the trk receptors are SHC, PI-3 kinase, and PLCG1. Four alternatively spliced isoforms are known.

Protein type: EC 2.7.10.1; Kinase, protein; Membrane protein, integral; Protein kinase, tyrosine (receptor); Protein kinase, TK; TK group; Trk family

Cellular Component: membrane; integral to plasma membrane; cytoplasm; integral to membrane; plasma membrane; receptor complex

Molecular Function: transferase activity; protein binding; ephrin receptor binding; p53 binding; protein-tyrosine kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; transmembrane receptor protein tyrosine kinase activity; neurotrophin receptor activity; ATP binding; protein kinase activity

Biological Process: nervous system development; mechanoreceptor differentiation; positive regulation of positive chemotaxis; activation of MAPK activity; positive regulation of axon extension involved in regeneration; protein amino acid autophosphorylation; multicellular organismal development; activation of protein kinase B; neuron migration; positive regulation of peptidyl-serine phosphorylation; protein amino acid phosphorylation; negative regulation of protein amino acid phosphorylation; positive regulation of cell proliferation; negative regulation of astrocyte differentiation; neuron fate specification; cell differentiation; phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway; positive regulation of cell migration

Research Articles on Ntrk3

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Product Notes

The Ntrk3 ntrk3 (Catalog #AAA9200051) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Ntrk3 Antibody reacts with Human, mouse, rat and may cross-react with other species as described in the data sheet. AAA Biotech's Ntrk3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the Ntrk3 ntrk3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Ntrk3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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