Western Blot (WB)
(All lanes : Anti-Ntrk3 Antibody at 1:1000 dilutionLane 1: human brain lysatesLane 2: mouse brain lysatesLane 3: rat brain lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Mouse IgG, (H+L),Peroxidase conjugated at 1/10000 dilutionPredicted band size : 93 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Mouse Ntrk3 Monoclonal Antibody | anti-Ntrk3 antibody
Ntrk3 Antibody
Western Blot (WB)
(All lanes : Anti-Ntrk3 Antibody at 1:1000 dilutionLane 1: human brain lysatesLane 2: mouse brain lysatesLane 3: rat brain lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Mouse IgG, (H+L),Peroxidase conjugated at 1/10000 dilutionPredicted band size : 93 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Western Blot (WB)
(All lanes : Anti-Ntrk3 Antibody at 1:1000 dilutionLane 1: human brain lysatesLane 2: mouse brain lysatesLane 3: rat brain lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Mouse IgG, (H+L),Peroxidase conjugated at 1/10000 dilutionPredicted band size : 93 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Background: Receptor for neurotrophin-3 (NT-3). This is a tyrosine- protein kinase receptor. Known substrates for the Trk receptors are SHC1, PI 3-kinase, and PLC-gamma-1 (By similarity).
NCBI and Uniprot Product Information
Uniprot Description
Function: Receptor for neurotrophin-3 (NT-3). This is a tyrosine-protein kinase receptor. Known substrates for the Trk receptors are SHC1, PI 3-kinase, and PLC-gamma-1
By similarity.
Catalytic activity: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
Subunit structure: Exists in a dynamic equilibrium between monomeric (low affinity) and dimeric (high affinity) structures. Binds SH2B2. Interacts with SQSTM1 and KIDINS220
By similarity.
Subcellular location: Membrane; Single-pass type I membrane protein
By similarity.
Tissue specificity: Isoform 2 expression is restricted to specific areas in adult brain. Isoform 3 transcripts are readily detected early during embryogenesis and are expressed predominantly in adult brain and gonads. Ref.2
Post-translational modification: Ligand-mediated auto-phosphorylation
By similarity.
Sequence similarities: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.Contains 2 Ig-like C2-type (immunoglobulin-like) domains.Contains 2 LRR (leucine-rich) repeats.Contains 1 LRRCT domain.Contains 1 protein kinase domain.
Research Articles on Ntrk3
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Product Notes
The Ntrk3 ntrk3 (Catalog #AAA9231962) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Ntrk3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Ntrk3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000. Researchers should empirically determine the suitability of the Ntrk3 ntrk3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Ntrk3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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