Western Blot (WB)
(Mouse Ntrk3 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Ntrk3 antibody detected the Ntrk3 protein (arrow).)
Rabbit anti-Mouse Ntrk3 Polyclonal Antibody | anti-Ntrk3 antibody
Ntrk3, NT (Ntrk3, TrkC, NT-3 growth factor receptor, GP145-TrkC, Neurotrophic tyrosine kinase receptor type 3, TrkC tyrosine kinase) (PE)
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Western Blot (WB)
(Mouse Ntrk3 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Ntrk3 antibody detected the Ntrk3 protein (arrow).)
Western Blot (WB)
(Mouse Ntrk3 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Ntrk3 antibody detected the Ntrk3 protein (arrow).)
Immunohistochemistry (IHC)
(Mouse Ntrk3 Antibody (N-term) (AP14627a)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Ntrk3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(Mouse Ntrk3 Antibody (N-term) (AP14627a)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Ntrk3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
NCBI and Uniprot Product Information
Uniprot Description
Function: Receptor for neurotrophin-3 (NT-3). This is a tyrosine-protein kinase receptor. Known substrates for the Trk receptors are SHC1, PI 3-kinase, and PLC-gamma-1
By similarity.
Catalytic activity: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
Subunit structure: Exists in a dynamic equilibrium between monomeric (low affinity) and dimeric (high affinity) structures. Binds SH2B2. Interacts with SQSTM1 and KIDINS220
By similarity.
Subcellular location: Membrane; Single-pass type I membrane protein
By similarity.
Tissue specificity: Isoform 2 expression is restricted to specific areas in adult brain. Isoform 3 transcripts are readily detected early during embryogenesis and are expressed predominantly in adult brain and gonads. Ref.2
Post-translational modification: Ligand-mediated auto-phosphorylation
By similarity.
Sequence similarities: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.Contains 2 Ig-like C2-type (immunoglobulin-like) domains.Contains 2 LRR (leucine-rich) repeats.Contains 1 LRRCT domain.Contains 1 protein kinase domain.
Research Articles on Ntrk3
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Product Notes
The Ntrk3 ntrk3 (Catalog #AAA6327028) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Ntrk3, NT (Ntrk3, TrkC, NT-3 growth factor receptor, GP145-TrkC, Neurotrophic tyrosine kinase receptor type 3, TrkC tyrosine kinase) (PE) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Ntrk3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), FLISA, Western Blot (WB). IHC: 1:10-50 FLISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the Ntrk3 ntrk3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Ntrk3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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