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Western Blot (WB) (Mouse Ntrk3 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Ntrk3 antibody detected the Ntrk3 protein (arrow).)

Rabbit Ntrk3 Polyclonal Antibody | anti-Ntrk3 antibody

Mouse Ntrk3 Antibody (N-term)

Gene Names
Ntrk3; TrkC; AW125844; Ntrk3_tv3
Reactivity
Mouse (Predicted Reactivity: Rat)
Applications
Western Blot, ELISA, Immunohistochemistry
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
Ntrk3; Polyclonal Antibody; Mouse Ntrk3 Antibody (N-term); NT-3 growth factor receptor; GP145-TrkC; Trk-C; Neurotrophic tyrosine kinase receptor type 3; TrkC tyrosine kinase; TrkC; anti-Ntrk3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse (Predicted Reactivity: Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This Mouse Ntrk3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-188 amino acids from the N-terminal region of mouse Ntrk3.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.4 (varies by lot)
Sequence Positions
161-188
Sequence Length
612
Applicable Applications for anti-Ntrk3 antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
MOUSE
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Mouse Ntrk3 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Ntrk3 antibody detected the Ntrk3 protein (arrow).)

Western Blot (WB) (Mouse Ntrk3 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Ntrk3 antibody detected the Ntrk3 protein (arrow).)

Immunohistochemistry (IHC)

(Mouse Ntrk3 Antibody (N-term) (MBS9214296)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Ntrk3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (Mouse Ntrk3 Antibody (N-term) (MBS9214296)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Ntrk3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-Ntrk3 antibody
Ntrk3 is a receptor for neurotrophin-3 (NT-3). This is a tyrosine-protein kinase receptor. Known substrates for the Trk receptors are SHC1, PI 3-kinase, and PLC-gamma-1 (By similarity).
Product Categories/Family for anti-Ntrk3 antibody
References
Gascon, E., et al. J. Neurosci. 30(37):12414-12423(2010)
Nikoletopoulou, V., et al. Nature 467(7311):59-63(2010)
Honma, Y., et al. Development 137(14):2319-2328(2010)
Huang, T., et al. J Mol Cell Biol 2(3):152-163(2010)
Li, W., et al. BMC Biol. 8, 86 (2010) :

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
92760
NCBI Official Full Name
NT-3 growth factor receptor isoform a
NCBI Official Synonym Full Names
neurotrophic tyrosine kinase, receptor, type 3
NCBI Official Symbol
Ntrk3
NCBI Official Synonym Symbols
TrkC; AW125844; Ntrk3_tv3
NCBI Protein Information
NT-3 growth factor receptor
UniProt Protein Name
NT-3 growth factor receptor
UniProt Gene Name
Ntrk3
UniProt Synonym Gene Names
TrkC; Trk-C
UniProt Entry Name
NTRK3_MOUSE

Uniprot Description

TrkC: a receptor tyrosine kinase of the TRK family. Receptor for neurotrophin-3 (NT-3). Known substrates for the trk receptors are SHC, PI-3 kinase, and PLCG1. Four alternatively spliced isoforms are known.

Protein type: Kinase, protein; Membrane protein, integral; EC 2.7.10.1; Protein kinase, tyrosine (receptor); Protein kinase, TK; TK group; Trk family

Cellular Component: membrane; integral to plasma membrane; cytoplasm; plasma membrane; integral to membrane; receptor complex

Molecular Function: transferase activity; protein binding; ephrin receptor binding; p53 binding; protein-tyrosine kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; transmembrane receptor protein tyrosine kinase activity; kinase activity; neurotrophin receptor activity; ATP binding; protein kinase activity

Biological Process: nervous system development; mechanoreceptor differentiation; positive regulation of positive chemotaxis; activation of MAPK activity; multicellular organismal development; positive regulation of axon extension involved in regeneration; protein amino acid autophosphorylation; activation of protein kinase B; neuron migration; positive regulation of peptidyl-serine phosphorylation; protein amino acid phosphorylation; negative regulation of protein amino acid phosphorylation; negative regulation of astrocyte differentiation; positive regulation of cell proliferation; neuron fate specification; cell differentiation; phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway; positive regulation of cell migration

Research Articles on Ntrk3

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Product Notes

The Ntrk3 ntrk3 (Catalog #AAA9214296) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 161-188. The Mouse Ntrk3 Antibody (N-term) reacts with Mouse (Predicted Reactivity: Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's Ntrk3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the Ntrk3 ntrk3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Ntrk3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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