Western Blot (WB)
(TGM3 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the TGM3 antibody detected the TGM3 protein (arrow).)
Rabbit anti-Human TGM3 Polyclonal Antibody | anti-TGM3 antibody
TGM3, CT (TGM3, Protein-glutamine gamma-glutamyltransferase E, Transglutaminase E, Transglutaminase-3, Protein-glutamine gamma-glutamyltransferase E 50kD catalytic chain, Protein-glutamine gamma-glutamyltransferase E 27kD non-catalytic chain)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Western Blot (WB)
(TGM3 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the TGM3 antibody detected the TGM3 protein (arrow).)
Western Blot (WB)
(TGM3 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the TGM3 antibody detected the TGM3 protein (arrow).)
NCBI and Uniprot Product Information
Uniprot Description
Function: Catalyzes the calcium-dependent formation of isopeptide cross-links between glutamine and lysine residues in various proteins, as well as the conjugation of polyamines to proteins. Involved in the formation of the cornified envelope (CE), a specialized component consisting of covalent cross-links of proteins beneath the plasma membrane of terminally differentiated keratinocytes. Catalyzes small proline-rich proteins and LOR cross-linking to form small interchain oligomers, which are further cross-linked by TGM1 onto the growing CE scaffold. In hair follicles, involved in cross-linking structural proteins to hardening the inner root sheath
By similarity.
Catalytic activity: Protein glutamine + alkylamine = protein N(5)-alkylglutamine + NH3.
Cofactor: Binds 1 calcium ion per subunit
By similarity.
Subunit structure: Consists of two polypeptide chains, which are synthesized as a precursor form of a single polypeptide
By similarity.
Post-translational modification: Activated by proteolytic processing. In vitro activation is commonly achieved by cleavage with dispase, a neutral bacterial protease. Physiological activation may be catalyzed by CTSL and, to a lesser extent, by CTSS
By similarity.
Sequence similarities: Belongs to the transglutaminase superfamily. Transglutaminase family.
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Product Notes
The TGM3 tgm3 (Catalog #AAA647112) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TGM3, CT (TGM3, Protein-glutamine gamma-glutamyltransferase E, Transglutaminase E, Transglutaminase-3, Protein-glutamine gamma-glutamyltransferase E 50kD catalytic chain, Protein-glutamine gamma-glutamyltransferase E 27kD non-catalytic chain) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TGM3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500. Researchers should empirically determine the suitability of the TGM3 tgm3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TGM3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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