Rabbit anti-Human LAIR2 Monoclonal Antibody | anti-LAIR2 antibody
Recombinant Anti-LAIR2 Antibody, Rabbit Monoclonal
Gene Names
LAIR2; CD306
Reactivity
Human
Applications
ELISA
Purity
Protein A
Synonyms
LAIR2; Monoclonal Antibody; Recombinant Anti-LAIR2 Antibody; Rabbit Monoclonal; LAIR2 Antibody; Rabbit MAb; leukocyte associated immunoglobulin like receptor 2; Anti-CD306 Antibody; Anti-LAIR2 Antibody; Anti-MGC71634 Antibody; Anti-XXbac-BCX535A19.6 Antibody; anti-LAIR2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone Number
024
Specificity
Human LAIR2
Purity/Purification
Protein A
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-LAIR2 antibody
ELISA (EIA)
Application Notes
ELISA: 1:5000-1:10,000
Antibody Type
Recombinant Antibody
Immunogen
Recombinant Human LAIR2 Protein
Conjugation
Unconjugated
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Human LAIR2 (rh LAIR2).
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Related Product Information for anti-LAIR2 antibody
Leukocyte-associated immunoglobulin-like receptor 2 (LAIR2), also known as CD36, is a 131 amino acid protein containing one Ig-like C2-type domain. It is expressed as a soluble receptor exhibiting high affinity for various collagen molecules to which it binds in a hydroxyproline-dependent manner. LAIR2 is a member of the immunoglobulin superfamily and was identified by its similarity to LAIR1, an inhibitory receptor present on mononuclear leukocytes. LAIR2 is thought to be secreted and may help modulate mucosal tolerance. As a natural competitor for LAIR1, soluble LAIR2 prevents binding of human LAIR1 to collagens and LAIR1 cross-linking, thereby regulating its inhibitory potential. Accordingly, LAIR2 is suggested to perform an immunoregulatory function.
Product Categories/Family for anti-LAIR2 antibody
References
Meyaard, L. et al., 1997, Immunity.7:283-290. Meyaard, L. et al., 1999, J. Immunol. 162:5800-5804. Meyaard, L. et al., 2001, J. Exp. Med. 194 (1): 107-112. Meyaard, L., 2003, J Biol Regul Homeost Agents. 17 (4): 330-333. Lebbink, R. J. et al., 2008, J Immunol. 180 (3):1662-1669. Lebbink, R.J. et al., 2009, Matrix Biol. 28 (4):202-210.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
14,722 Da
NCBI Official Full Name
leukocyte-associated immunoglobulin-like receptor 2 isoform a
NCBI Official Synonym Full Names
leukocyte-associated immunoglobulin-like receptor 2
NCBI Official Symbol
LAIR2
NCBI Official Synonym Symbols
CD306
NCBI Protein Information
leukocyte-associated immunoglobulin-like receptor 2; LAIR-2; leukocyte-associated Ig-like receptor 2; leukocyte-associated Ig-like receptor-2
UniProt Protein Name
Leukocyte-associated immunoglobulin-like receptor 2
Protein Family
UniProt Gene Name
LAIR2
UniProt Synonym Gene Names
CD306; LAIR-2
UniProt Entry Name
LAIR2_HUMAN
NCBI Description
The protein encoded by this gene is a member of the immunoglobulin superfamily. It was identified by its similarity to leukocyte-associated immunoglobulin-like receptor 1, a membrane-bound receptor that modulates innate immune response. The protein encoded by this locus is a soluble receptor that may play roles in both inhibition of collagen-induced platelet aggregation and vessel formation during placental implantation. This gene maps to a region of 19q13.4, termed the leukocyte receptor cluster, which contains 29 genes in the immunoglobulin superfamily. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2013]
Uniprot Description
LAIR-2: 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 19q13.4
Cellular Component: extracellular region
Research Articles on LAIR2
Similar Products
Product Notes
The LAIR2 lair2 (Catalog #AAA8104185) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Anti-LAIR2 Antibody, Rabbit Monoclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LAIR2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). ELISA: 1:5000-1:10,000. Researchers should empirically determine the suitability of the LAIR2 lair2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LAIR2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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