Mouse anti-Human IGFBP-1 Monoclonal Antibody | anti-IGFBP1 antibody
Anti-IGFBP-1 (Insulin-like Growth Factor-binding Protein 1, IBP-1, IGF-binding Protein 1, Placental Protein 12, PP12, IGFBP1, IBP1)
Gene Names
IGFBP1; AFBP; IBP1; PP12; IGF-BP25; hIGFBP-1
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity Purified
Synonyms
IGFBP-1; Monoclonal Antibody; Anti-IGFBP-1 (Insulin-like Growth Factor-binding Protein 1; IBP-1; IGF-binding Protein 1; Placental Protein 12; PP12; IGFBP1; IBP1); Insulin-like Growth Factor-binding Protein 1; IBP1; anti-IGFBP1 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
11C116
Specificity
Recognizes human IGFBP-1.
Purity/Purification
Affinity Purified
Form/Format
Supplied as a liquid, 0.05% sodium azide.
Concentration
~1mg/ml (varies by lot)
Applicable Applications for anti-IGFBP1 antibody
ELISA; Western Blot
Application Notes
Recommended Dilutions: Western Blot: 1:500-1:5000 (ECL)
ELISA: 0.5-1ug/ml
ELISA: 0.5-1ug/ml
Immunogen
Recombinant corresponding to human IGFBP-1, expressed in NSO cells.
Source Information
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Shipping Temperature: Blue Ice
Shipping Temperature: Blue Ice
Related Product Information for anti-IGFBP1 antibody
Unlike insulin, both IGF-I and IGF-II circulate in plasma tightly bound to specific binding proteins. Two major forms of IGF- binding proteins have been identified in human plasma, a low molecular weight form and a high molecular weight form. The low molecular weight IGF-binding protein (IGFBP1) is synthesized in liver, secretory endometrium, and decidua. It binds both IGF I and IGF II with high affinity. Insulin-like growth factor binding protein-1 (IGFBP-1 ~30kD; also known as IBP1 or placental protein 12, or IGF-BP25; chromosome 7p14-p12)) is a member of the superfamily of insulin-like growth factor (IGF) binding proteins which include six high-affinity IGF binding proteins (IGFBP1-6) and at least four low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP). The IGFBP members are cysteine- rich proteins with conserved cysteine residues, clustered in the amino-terminal and the carboxy-terminal regions of the molecule. Contained within IGFBP-1 and -2 is an integrin receptor recognition sequence (RGD) that is responsible for promoting cell migration by an IGF-independent action. IGFBPs hold a central position in IGF ligand-receptor interactions through influences on both the bioavailability and distribution of IGFs in the extracellular environment. IGFBPs will either inhibit or enhance the biological activities of IGF or act in an IGF-independent manner.
Product Categories/Family for anti-IGFBP1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
27,904 Da
NCBI Official Full Name
insulin-like growth factor-binding protein 1
NCBI Official Synonym Full Names
insulin-like growth factor binding protein 1
NCBI Official Symbol
IGFBP1
NCBI Official Synonym Symbols
AFBP; IBP1; PP12; IGF-BP25; hIGFBP-1
NCBI Protein Information
insulin-like growth factor-binding protein 1; IBP-1; IGFBP-1; OTTHUMP00000159561; OTTHUMP00000207990; OTTHUMP00000214348; binding protein-25; binding protein-26; binding protein-28; placental protein 12; IGF-binding protein 1; amniotic fluid binding protein; growth hormone independent-binding protein; alpha-pregnancy-associated endometrial globulin
UniProt Protein Name
Insulin-like growth factor-binding protein 1
Protein Family
UniProt Gene Name
IGFBP1
UniProt Synonym Gene Names
IBP1
UniProt Entry Name
IBP1_HUMAN
Similar Products
Product Notes
The IGFBP1 igfbp1 (Catalog #AAA631717) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-IGFBP-1 (Insulin-like Growth Factor-binding Protein 1, IBP-1, IGF-binding Protein 1, Placental Protein 12, PP12, IGFBP1, IBP1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IGFBP-1 can be used in a range of immunoassay formats including, but not limited to, ELISA; Western Blot. Recommended Dilutions: Western Blot: 1:500-1:5000 (ECL) ELISA: 0.5-1ug/ml. Researchers should empirically determine the suitability of the IGFBP1 igfbp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IGFBP-1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
