Mouse anti-Human CTRP1 Monoclonal Antibody | anti-C1QTNF1 antibody

CTRP1 (C1q Tumor Necrosis Factor alpha Related Protein 1, C1qTNF1)

Cat. Num. AAA603569

• Gene Names: C1QTNF1; GIP; CTRP1; ZSIG37; FLJ90694
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Purified by Protein G affinity chromatography.
• Synonyms: CTRP1; Monoclonal Antibody; CTRP1 (C1q Tumor Necrosis Factor alpha Related Protein 1; C1qTNF1); Anti -CTRP1 (C1q Tumor Necrosis Factor alpha Related Protein 1; anti-C1QTNF1 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG2b
• Clone Number: 7H203
• Specificity: Recognizes human CTRP1. Does not crossreact with recombinant human CTRP4, CTRP5 or CTRP10.
• Purity/Purification: Purified by Protein G affinity chromatography.
• Form/Format: Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 200ul sterile PBS.
• Concentration: ~0.5mg/ml (after reconsitution) (varies by lot)

• Applicable Applications for anti-C1QTNF1 antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Dilution: Western Blot: 1-2ug/ml. Using a colormetric detection system, the detection limit is ~5ng/lane under non-reducing and reducing conditions.; ELISA (Direct): 0.5-1ug/ml. The detection limit is ~1ng/well.; Optimal diulutions to be determined by the researcher.
• Immunogen: Recombinant protein corresponding to aa26-281 from human CRTP1, expressed in NSO cells.; Species Sequence Homology: mouse 78%
• Grade: Affinity Purified
• Preparation and Storage: Lyophilized and reconstituted products are stable for 12 months after receipt at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Related Product Information for anti-C1QTNF1 antibody

CTRP1 belongs to the highly conserved family of Acrp30/Adiponectin paralogs known as the C1q and TNF-related protein family. All family members share a modular organization comprising an N-terminal signal peptide, a short variable region, a collagenous domain and a C-terminal globular domain. CTRP1 proteins are predicted to have trimeric structures that assemble into hexameric and higher order molecular forms.

Product Categories/Family for anti-C1QTNF1 antibody

Antibodies; Abs to Obesity Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 38372917
• NCBI GeneID: 114897
• NCBI Accession #: NP_940995.1
• NCBI GenBank Nucleotide #: NM_198593.2
• UniProt Accession #: Q9BXJ1; Q96NF2; Q9GZR4; Q6ZMH6
• NCBI Official Full Name: complement C1q tumor necrosis factor-related protein 1 isoform 1
• NCBI Official Synonym Full Names: C1q and tumor necrosis factor related protein 1
• NCBI Official Symbol: C1QTNF1
• NCBI Official Synonym Symbols: GIP; CTRP1; ZSIG37; FLJ90694
• NCBI Protein Information: complement C1q tumor necrosis factor-related protein 1; G protein coupled receptor interacting protein; g protein-coupled receptor-interacting protein
• UniProt Protein Name: Complement C1q tumor necrosis factor-related protein 1
• Protein Family: Complement C1q tumor necrosis factor-related protein
• UniProt Gene Name: C1QTNF1
• UniProt Synonym Gene Names: CTRP1
• UniProt Entry Name: C1QT1_HUMAN

Uniprot Description

C1QTNF1: 2 isoforms of the human protein are produced by alternative splicing

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 17q25.3

Cellular Component: extracellular space; collagen; integral to plasma membrane

Molecular Function: collagen binding; protein binding

Biological Process: positive regulation of protein kinase B signaling cascade; elevation of cytosolic calcium ion concentration; positive regulation of MAPKKK cascade; protein homooligomerization