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Flow Cytometry (FC/FACS) (Flow cytometry antibody)

Mouse anti-Human CD81 Monoclonal Antibody | anti-CD81 antibody

Anti-Human CD81 Monoclonal Antibody (PerCP/Cy5.5 Conjugated)

Gene Names
CD81; S5.7; CVID6; TAPA1; TSPAN28
Reactivity
Human
Applications
Flow Cytometry, Functional Assay
Synonyms
CD81; Monoclonal Antibody; Anti-Human CD81 Monoclonal Antibody (PerCP/Cy5.5 Conjugated); CD81 antigen; 26 kDa cell surface protein TAPA-1; Target of the antiproliferative antibody 1.Tetraspanin-28; Tspan-28; APA1; TSPAN28; anti-CD81 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1.3.3.22
Form/Format
Liquid; PBS with 0.05% Proclin300, 1% BSA
Sequence Length
236
Applicable Applications for anti-CD81 antibody
Flow Cytometry (FC/FACS)
Conjugation
PerCP/Cy5.5
Preparation and Storage
Store at 2-8 degree C and protected from prolonged exposure to light. Do not freeze.

Flow Cytometry (FC/FACS)

(Flow cytometry antibody)

Flow Cytometry (FC/FACS) (Flow cytometry antibody)

Flow Cytometry (FC/FACS)

(Human peripheral blood lymphocytes are stained with Anti-Human CD81 Monoclonal Antibody(PerCP/Cy5.5 Conjugated)(filled gray histogram). Unstained lymphocytes (empty black histogram) are used as control.)

Flow Cytometry (FC/FACS) (Human peripheral blood lymphocytes are stained with Anti-Human CD81 Monoclonal Antibody(PerCP/Cy5.5 Conjugated)(filled gray histogram). Unstained lymphocytes (empty black histogram) are used as control.)
Related Product Information for anti-CD81 antibody
CD81 is a 26 kD non-glycosylated member of the tetraspanin superfamily (TM4SF), also known as TAPA-1 (target of an antiproliferative antibody). CD81 is expressed on T and B cells, NK cells, monocytes, dendritic cells, thymocytes, endothelial cells, and fibroblasts. It also has low levels of expression on granulocytes. CD81 induces B cell adhesion via VLA-4 integrin and has been shown to play a role in early T cell development. CD81 associates with several other cell-surface proteins in a multimolecular complex, including CD19, CD21, CD20, CD37, CD53, and CD82 in B cells, and CD4, CD8 and CD82 in T cells.
References
1. Menno C, et al. 2010. J. Clin. Invest. 4:1265. 2. Fearon D, et al. 1995. Annu. Rev. Immunol. 13:127. 3. Wright M, et al. 1994. Immunol. Today 15:588.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
975
UniProt Accession #
NCBI Official Full Name
CD81 antigen
NCBI Official Synonym Full Names
CD81 molecule
NCBI Official Symbol
CD81
NCBI Official Synonym Symbols
S5.7; CVID6; TAPA1; TSPAN28
NCBI Protein Information
CD81 antigen
UniProt Protein Name
CD81 antigen
Protein Family
UniProt Gene Name
CD81
UniProt Synonym Gene Names
TAPA1; TSPAN28; Tspan-28

NCBI Description

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

Uniprot Description

May play an important role in the regulation of lymphoma cell growth. Interacts with a 16-kDa Leu-13 protein to form a complex possibly involved in signal transduction. May act as the viral receptor for HCV.(Microbial infection) Acts as a receptor for hepatitis C virus (HCV) in hepatocytes. Associates with CLDN1 and the CLDN1-CD81 receptor complex is essential for HCV entry into host cell.

Research Articles on CD81

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Product Notes

The CD81 cd81 (Catalog #AAA2556881) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-Human CD81 Monoclonal Antibody (PerCP/Cy5.5 Conjugated) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD81 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). Researchers should empirically determine the suitability of the CD81 cd81 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD81, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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