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Mouse 4-Amino Biphenyl DNA Monoclonal Antibody

4-Amino Biphenyl DNA (4-AMBP DNA, 4-Aminobiphenyl DNA)

Applications
ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence
Purity
Affinity Purified
Purified by Protein G affinity chromatography.
Synonyms
4-Amino Biphenyl DNA; Monoclonal Antibody; 4-Amino Biphenyl DNA (4-AMBP DNA; 4-Aminobiphenyl DNA); Anti -4-Amino Biphenyl DNA (4-AMBP DNA; anti-4-Amino Biphenyl DNA antibody
Ordering
For Research Use Only!
Host
Mouse
Clonality
Monoclonal
Clone Number
8J250
Specificity
This antibody is specific for 4-amino Biphenyl DNA. Crossreactivity: All DNAs
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Form/Format
Supplied as a liquid (ascites).
Applicable Applications for anti-4-Amino Biphenyl DNA antibody
ELISA (EL/EIA), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes
Suitable for use in Immunofluorescence, ELISA, Immunohistochemistry and Immunocytochemistry.
Dilution: ELISA: 1:50-1:100
Immunohistochemistry: 1:50-1:100
Immunocytochemistry: 1:50-1:100
Immunofluorescence: 1:50-1:100
Immunogen
4-amino Biphenyl DNA.
Cellular Localization
Nuclear
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-4-Amino Biphenyl DNA antibody
4-amino Biphenyl (4-ABP) is an aromatic amine (arylamine). 4-ABP can be found as a constituent of tobacco smoke, in the form of an environmental carcinogen. It is metabolized by hepatic cytochrome P4501A2 to yield a direct-acting mutagen known as N-hydroxy-aminobiphenyl. Yet, the accumulation of biologically active metabolites is dependent on the activation and detoxification of N-acetylation.

4-ABP has been shown to be a bladder carcinogen in humans and rodents. As well as genetic factors, 4-ABP may also play a role in breast cancer. It is hypothesized that smokers may have higher levels of DNA adducts than non-smokers and that the role of 4-ABP-DNA adducts and their relationship to tobacco exposure may be related to breast tumorigenesis. The antibody has been used to investigate the role of 4-ABP in the study of human breast cancer by measuring 4-ABP-DNA adducts.
Product Categories/Family for anti-4-Amino Biphenyl DNA antibody

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Product Notes

The 4-Amino Biphenyl DNA (Catalog #AAA600356) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's 4-Amino Biphenyl DNA can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF). Suitable for use in Immunofluorescence, ELISA, Immunohistochemistry and Immunocytochemistry. Dilution: ELISA: 1:50-1:100 Immunohistochemistry: 1:50-1:100 Immunocytochemistry: 1:50-1:100 Immunofluorescence: 1:50-1:100. Researchers should empirically determine the suitability of the 4-Amino Biphenyl DNA for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "4-Amino Biphenyl DNA, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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