Rat Lysophosphatidic acid receptor 1 ELISA Kit | Lpar1 elisa kit
Rat Lysophosphatidic acid receptor 1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
G-protein coupled receptor for lysophosphatidic acid (LPA); may mediate LPA induced increase in intracellular calcium ion concentration [RGD, Feb 2006]
Uniprot Description
LPAR1: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Stimulates phospholipase C (PLC) activity in a manner that is dependent on RALA activation. Belongs to the G-protein coupled receptor 1 family.
Protein type: Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1; Membrane protein, integral
Cellular Component: cell soma; cell surface; cytoplasm; cytosol; dendritic shaft; dendritic spine; endocytic vesicle; endosome; integral to plasma membrane; neuron projection; plasma membrane
Molecular Function: G-protein alpha-subunit binding; G-protein coupled receptor activity; PDZ domain binding; phospholipid binding
Biological Process: activation of MAPK activity; bleb formation; brain development; cerebellum development; corpus callosum development; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); G-protein coupled receptor protein signaling pathway; G-protein signaling, adenylate cyclase inhibiting pathway; myelination; negative regulation of cAMP biosynthetic process; neurogenesis; oligodendrocyte development; optic nerve development; phospholipase C activation; positive regulation of apoptosis; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of MAPKKK cascade; positive regulation of Rho protein signal transduction; positive regulation of stress fiber formation; regulation of cell shape
Research Articles on Lpar1
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Product Notes
The Rat Lpar1 lpar1 (Catalog #AAA2883870) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2883870 ELISA Kit recognizes Rat Lpar1. It is sometimes possible for the material contained within the vial of "Lysophosphatidic acid receptor 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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