Immunohistochemistry (IHC)
(Anti-Kallikrein 2 antibody, MBS175260, IHC(P)IHC(P): Human Prostatic Cancer Tissue )
Rabbit anti-Human Kallikrein 2 Polyclonal Antibody | anti-KLK2 antibody
Anti-Kallikrein 2 antibody
Immunohistochemistry (IHC)
(Anti-Kallikrein 2 antibody, MBS175260, IHC(P)IHC(P): Human Prostatic Cancer Tissue )
Immunohistochemistry (IHC)
(Anti-Kallikrein 2 antibody, MBS175260, IHC(P)IHC(P): Human Prostatic Cancer Tissue )
Western Blot (WB)
(Anti-Kallikrein 2 antibody, MBS175260, Western blottingAll lanes: Anti Kallikrein 2 (MBS175260) at 0.5ug/mlLane 1: PANC Whole Cell Lysate at 40ugLane 2: HELA Whole Cell Lysate at 40ugLane 3: 293T Whole Cell Lysate at 40ugPredicted bind size: 29KDObserved bind size: 29KD )
Western Blot (WB)
(Anti-Kallikrein 2 antibody, MBS175260, Western blottingAll lanes: Anti Kallikrein 2 (MBS175260) at 0.5ug/mlLane 1: PANC Whole Cell Lysate at 40ugLane 2: HELA Whole Cell Lysate at 40ugLane 3: 293T Whole Cell Lysate at 40ugPredicted bind size: 29KDObserved bind size: 29KD )
Background: KLK2(KALLIKREIN 2), also called GLANDULAR or PROSTATIC, is a protein that in humans is encoded by the KLK2 gene, and is particularly associated with prostatic tissue. The KLK2 is a member of glandular kallikrein gene family that comprises 25 to 30 highly homologous genes that encode specific proteases involved in the processing of biologically active peptides. The KLK2 gene is mapped to 19q13.33. And the KLK2 gene contains 5 exons. An alternative KLK2 transcript, which they call KLK2-linked molecule(KLM), that arises from the use of an alternate donor site within intron 1. KLM shares only the N-terminal 15-amino acid signal peptide with the original KLK2 protein; the mature proteins display no similarity.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Jan 2012]
Uniprot Description
KLK2: Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Belongs to the peptidase S1 family. Kallikrein subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Protease; EC 3.4.21.35
Chromosomal Location of Human Ortholog: 19q13.41
Cellular Component: extracellular region
Molecular Function: serine-type endopeptidase activity
Biological Process: extracellular matrix disassembly; extracellular matrix organization and biogenesis; proteolysis
Research Articles on KLK2
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Product Notes
The KLK2 klk2 (Catalog #AAA175260) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Kallikrein 2 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Kallikrein 2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin. Researchers should empirically determine the suitability of the KLK2 klk2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Kallikrein 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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