Human killer cell lectin-like receptor subfamily C, member 3 ELISA Kit | KLRC3 elisa kit
Human NKG2-E type II integral membrane protein, KLRC3 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC3 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Uniprot Description
KLRC3: Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 12p13
Cellular Component: integral to membrane
Molecular Function: transmembrane receptor activity; carbohydrate binding
Biological Process: cellular defense response; signal transduction
Research Articles on KLRC3
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Product Notes
The Human KLRC3 klrc3 (Catalog #AAA9321514) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9321514 ELISA Kit recognizes Human KLRC3. It is sometimes possible for the material contained within the vial of "killer cell lectin-like receptor subfamily C, member 3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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