Molecular Structure
Sunitinib malate, Inhibitor
Sunitinib malate
Purity
>98% (TLC); NMR conforms
Synonyms
Sunitinib malate; SP-600125; Anthra [1-9-cd] pyrazol-6(2H)-one; 1; 9-Pyrazoloanthrone; inhibitor
Purity/Purification
>98% (TLC); NMR conforms
Form/Format
Yellow powder
CAS Number
129-56-6
Molecular Formula
C14H8N2O
Melting Point
290 degree C
Activity
JNK inhibitor
Reconstitution
May be dissolved in DMSO (22 mg/ml); or Ethanol (2 mg/ml)
Preparation and Storage
Store as supplied at ambient temperature for up to 2 years. Store solutions at -20 degree C for up to 3 months.
Molecular Structure
Molecular Structure
Related Product Information for Sunitinib malate, inhibitor
VEGFR; PDGFR inhibitor
Selective inhibitor of c-Jun N-terminal kinase (JNK). Reversibly inhibits JNK1,2 and 3 (IC50=40-90 nM) with >300-fold selectivity against related MAP kinases. Anti-inflammatory activity. Inhibits expression of presenilin-1 and Notch signaling in mouse brain. Cell permeable. Active in vivo.
Selective inhibitor of c-Jun N-terminal kinase (JNK). Reversibly inhibits JNK1,2 and 3 (IC50=40-90 nM) with >300-fold selectivity against related MAP kinases. Anti-inflammatory activity. Inhibits expression of presenilin-1 and Notch signaling in mouse brain. Cell permeable. Active in vivo.
Product Categories/Family for Sunitinib malate, inhibitor
References
BL Bennett et al. Proc. Natl. Acad. Sci. USA. 2001 98:13681
M Rahman et al. Brain Res. 2012 1448:117
M Rahman et al. Brain Res. 2012 1448:117
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Product Notes
The Sunitinib malate (Catalog #AAA515034) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Sunitinib malate, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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