Structure
ITX-5061, Inhibitor
ITX-5061
Purity
>98% (HPLC)
Synonyms
ITX-5061; ITX5061; inhibitor
Purity/Purification
>98% (HPLC)
Target
Scavenger Receptor
Receptor
Scavenger Receptor
Chemical Name
N-(5-(tert-butyl)-2-methoxy-3-(methylsulfonamido)phenyl)-2-(4-(2-morpholinoethoxy)naphthalen-1-yl)-2-oxoacetamide
SMILES
CC(C)(C)C1=CC(=C(C(=C1)NS(=O)(=O)C)OC)NC(=O)C(=O)C2=CC=C(C3=CC=CC=C32)OCCN4CCOCC4
Molecular Formula
C30H37N3O7S
CAS Number
848144-15-0
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for ITX-5061, inhibitor
ITX-5061 is a scavenger receptor B1 antagonist that promotes high-density lipoprotein (HDL) levels; inhibits SR-BI-dependent uptake of HDL-CE in transfected cells, decreases the fractional catabolic rate of HDL-CE and reduced its hepatic uptake in mice; inhibits HCVcc and HCVpp infection of primary human hepatocytes and/or human hepatoma cell lines and has minimal effects on HCV RNA replication. HCV Infection Phase 2 Clinical
Product Categories/Family for ITX-5061, inhibitor
References
1. Masson D, et al. Arterioscler Thromb Vasc Biol. 2009 Dec; 29 (12):2054-60.
2. Zhu H, et al. J Infect Dis. 2012 Feb 15; 205 (4):656-62.
3. Syder AJ, et al. J Hepatol. 2011 Jan; 54 (1):48-55.
2. Zhu H, et al. J Infect Dis. 2012 Feb 15; 205 (4):656-62.
3. Syder AJ, et al. J Hepatol. 2011 Jan; 54 (1):48-55.
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Product Notes
The ITX-5061 (Catalog #AAA3606155) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ITX-5061, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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