Structure
GATA4-IN-3, Inhibitor
GATA4-IN-3
Purity
>98% (HPLC)
Synonyms
GATA4-IN-3; GATA4 inhibitor 3; inhibitor
Purity/Purification
>98% (HPLC)
Target
GATA Binding Protein
Receptor
GATA Binding Protein
Chemical Name
N-[4-(diethylamino)phenyl]-5-methyl-3-phenylisoxazole-4-carboxamide
SMILES
CC1=C(C(NC2=CC=C(N(CC)CC)C=C2)=O)C(C3=CC=CC=C3)=NO1
Molecular Formula
C21H23N3O2
CAS Number
544681-96-1
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for GATA4-IN-3, inhibitor
A novel small molecule that inhibits GATA4/NKX2-5 transcriptional synergy with IC50 of 3uM, with no activity on the protein kinases involved in the regulation of GATA4 phosphorylation; also inhibits the ET-1-stimulated BNP gene expression, and inhibits hypertrophic growth in a cardiomyocyte hypertrophy model, without effect on apoptotic cell death.
Product Categories/Family for GATA4-IN-3, inhibitor
References
1. Vlimki MJ, et al. J Med Chem. 2017 Sep 28; 60 (18):7781-7798.
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Product Notes
The GATA4-IN-3 (Catalog #AAA3604954) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "GATA4-IN-3, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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