Testing Data
Decitabine, Inhibitor
Decitabine
Purity
>98%
Synonyms
Decitabine; 5-Aza-2'-deoxycytidine; NSC-127716; inhibitor
Purity/Purification
>98%
Specific Activity
DNA Methyl Transferase Inhibitor
CAS Registry Number
2353-33-5
Molecular Formula
C8H12N4O4
Melting Point
193-196 degree C
Solubility
May be dissolved in DMSO (25mg/ml); or water (11mg/ml). Ethanol (nil)
Preparation and Storage
Store desiccated as supplied at 4 degree C for up to 2 years. Store solutions at -20 degree C for up to 3 months.
Testing Data
Testing Data
Related Product Information for Decitabine, inhibitor
Inhibits DNA methyltransferase. Induces demethylation and reactivation of silenced genes suppressing the growth of human tumor cell lines1. Increases stem cell reprogramming efficiency. Stimulates osteogenic differentiation of human bone marrow stromal cells2. Induces differentiation and growth inhibition in IDH1 mutant gliomoa cells and decreases tumor growth in vivo3. Cell permeable.
Product Categories/Family for Decitabine, inhibitor
References
1. CM Bender et al. Cancer Res. 1998 58:95
2. AT El-Serafi et al. Differentiation 2011 81:35
3. S Turcan et al. Oncotarget 2013 4:1729
2. AT El-Serafi et al. Differentiation 2011 81:35
3. S Turcan et al. Oncotarget 2013 4:1729
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Product Notes
The Decitabine (Catalog #AAA516364) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Decitabine, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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