Structure
D-3263 hydrochloride, Inhibitor | D-3263, inhibitor
D-3263 hydrochloride
Purity
98.00%
Synonyms
D-3263 hydrochloride; D-3263; inhibitor
Purity/Purification
98.00%
Form/Format
Solid. Powder
Solubility
DMSO: 40mg/mL (97.57mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C21H32ClN3O3
SMILES
[H]Cl.O=C1N(CCN)C2=CC(OC)=CC=C2N1C([C@H]3[C@H](C(C)C)CC[C@@H](C)C3)=O
CAS Number
1008763-54-9
Target & IC50
Others
In Vitro
D-3263 hydrochloride binds and activates TRPM8, which may lead to increased entry of calcium and sodium; destruction of calcium and sodium homeostasis; induction of cell death in tumor cells expressing TRPM8. D-3263 hydrochloride may reduce the level of dihydrotestosterone (DHT), which may contribute to its inhibitory effect on prostate cancer and BPhours.
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
-80 degree C for 2 years in solvent
Structure
Structure
Related Product Information for D-3263, inhibitor
D-3263 hydrochloride is enteric-coated, orally bioavailable (transient receptor potential melatonin member 8) TRPM8 agonist.
References
enteric-coated TRPM8 agonist D-3263 hydrochloride
enteric-coated TRPM8 agonist D-3263 hydrochloride
enteric-coated TRPM8 agonist D-3263 hydrochloride
Similar Products
Product Notes
The D-3263 (Catalog #AAA5752969) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "D-3263 hydrochloride, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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