Structure

BRD4 inhibitor Compound V, Inhibitor

BRD4 inhibitor Compound V

Purity

>98% (HPLC)

Synonyms

BRD4 inhibitor Compound V; inhibitor

Ordering

Purity/Purification

>98% (HPLC)

Target

Bromodomain

Receptor

Bromodomain

Chemical Name

N-(3, 5-dimethylphenyl)-4-(4-(4-fluorophenyl)-1-(piperidin-4-yl)-1Himidazol-5-yl)pyrimidin-2-amine

Molecular Formula

C26H27FN6

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Structure

Related Product Information for BRD4 inhibitor Compound V, inhibitor

BRD4 inhibitor Compound V is a domain-selective inhibitor of BRD4 with IC50 of 1.8uM for BRD4 BD1, displays 6- and 16-fold selectivity for BRD4 over BRD2 and BRD3, respectively; demonstrates reduction of c-Myc expression, inhibition of NF-kappaB signaling, and suppression of IL-8 production through potential synergistic inhibition of BRD4 (1) and p38alpha.

Product Categories/Family for BRD4 inhibitor Compound V, inhibitor

Chromatin/Epigenetic

References

1. Anand Divakaran, et al. J. Med. Chem., 2018, 61 (20), pp 9316-9334.

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Product Notes

The BRD4 inhibitor Compound V (Catalog #AAA3607055) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "BRD4 inhibitor Compound V, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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BRD4 inhibitor Compound V, Inhibitor