Structure
CPI-637, Inhibitor
CPI-637
Purity
>98% (HPLC)
Synonyms
CPI-637; CPI637; CPI 637; inhibitor
Purity/Purification
>98% (HPLC)
Suitability
DMSO
Target
Bromodomain
Receptor
BRD4; CBP; EP300
Chemical Name
2H-1, 5-Benzodiazepin-2-one, 1, 3, 4, 5-tetrahydro-4-methyl-6-[1-methyl-3-(1-methyl-1H-pyrazol-4-yl)-1H-indazol-5-yl]-, (4R)
SMILES
CN(N=C1C2=CN(C)N=C2)C3=C1C=C(C4=CC=CC(N5)=C4N[C@H](C)CC5=O)C=C3
Molecular Formula
C22H22N6O
CAS Number
1884712-47-3
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for CPI-637, inhibitor
A potent and selective, cell-active CBP/EP300 bromodomain inhibitor with CBP BRET EC50 of 0.03uM; displays >700-fold selectivity over the BET bromodomains (BRD4 IC50=11.0uM), also highly selective against other bromodomains; inhibits the expression of MYC with an EC50 of 0.60uM in a cellular assay.
Product Categories/Family for CPI-637, inhibitor
References
1. Taylor AM, et al. ACS Med Chem Lett. 2016 Mar 15; 7 (5):531-6.
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Product Notes
The CPI-637 (Catalog #AAA3602946) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CPI-637, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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