Related Product Information for IL17F elisa kit
Principle of the assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for IL17F has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any IL17F present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for IL17F is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of IL17F bound in the initial step. The color development is stopped and the intensity of the color is measured.
Uniprot Description
IL17F: Stimulates the production of other cytokines such as IL- 6, IL-8 and granulocyte colony-stimulating factor, and can regulate cartilage matrix turnover. Stimulates PBMC and T-cell proliferation. Inhibits angiogenesis. Defects in IL17F are the cause of familial candidiasis type 6 (CANDF6). CANDF6 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans. Belongs to the IL-17 family.
Protein type: Cytokine; Secreted; Secreted, signal peptide
Cellular Component: extracellular space
Molecular Function: protein homodimerization activity; hematopoietin/interferon-class (D200-domain) cytokine receptor binding; cytokine binding; cytokine activity
Biological Process: proteoglycan metabolic process; negative regulation of angiogenesis; regulation of interleukin-8 biosynthetic process; regulation of transforming growth factor beta receptor signaling pathway; lymphotoxin A biosynthetic process; regulation of interleukin-2 biosynthetic process; regulation of granulocyte macrophage colony-stimulating factor biosynthetic process; cytokine biosynthetic process; cartilage development; regulation of interleukin-6 biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; inflammatory response
Product Notes
The Rat IL17F il17f (Catalog #
AAA936932) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA936932 ELISA Kit recognizes Rat IL17F.
It is sometimes possible for the material contained within the vial of
"interleukin 17F, ELISA Kit" to become dispersed throughout the inside of
the vial, particularly around the seal of said vial, during shipment and storage. We always
suggest centrifuging these vials
to consolidate all of the liquid away from the lid and to the bottom of the vial prior to
opening. Please be advised that
certain products may require dry ice for shipping and that, if this is the case, an
additional dry ice fee may also be
required.
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absolutely not suitable for use in any
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industry standard. AAA Biotech
and its authorized distribution partners reserve the right to refuse to fulfill any order if
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