ICAM-5 recombinant protein

Human CellExp ICAM-5

Cat. Num. AAA8400698

• Gene Names: ICAM5; TLN; TLCN
• Purity: >90% by SDS-PAGE
• Synonyms: ICAM-5; Human CellExp ICAM-5; FCGR3A; CD16A; FCG3; FCGR3; IGFR3; CD16; Fc gamma RIIIa; FCGRIII; FCR-10; FCRIIIA; IMD20; Fc receptor with low affinity for IgG; Intercellular adhesion molecule 5; ICAM5; Telencephalin; TLN; TLCN; ICAM-5 recombinant protein

• Host: HEK293 cells
• Specificity: A ligand for the leukocyte adhesion protein LFA-1
• Purity/Purification: >90% by SDS-PAGE
• Form/Format: Liquid
• Concentration: 0.5mg/ml (varies by lot)
• Sequence Positions: 23-835aa

• Source: Human
• Endotoxin Level: <1 EU per 1ug of protein (determined by LAL method)
• Preparation and Storage: Store at -20 degree C; Centrifuge the vial prior to opening.; Shipping: Gel Pack; Shelf Life: Est.~12 months; Country of Origin: USA

SDS-Page

Related Product Information for ICAM-5 recombinant protein

ICAM-5 is a cell surface glycoprotein belonging to the immunoglobulin superfamily. ICAM-5 is involved in adhesion and is a ligand for the leukocyte adhesion protein LFA-1, like other ICAMs. Human ICAM-5 is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes.

Product Categories/Family for ICAM-5 recombinant protein

Web Categories; Cancer Research; Growth Factors; Cytokines & Growth Factors (A-Z); Web Categories; Proteins and Enzymes; Proteins and Enzymes (A-Z); CDs; Cytokines; Growth Factors & Hormones; ICAMs; Human cell expressed recombinant proteins

NCBI and Uniprot Product Information

• NCBI GI #: 189571583
• NCBI GeneID: 7087
• NCBI Accession #: NP_003250
• NCBI GenBank Nucleotide #: NM_003259
• UniProt Accession #: Q9UMF0
• Molecular Weight: 95kDa
• NCBI Official Full Name: intercellular adhesion molecule 5
• NCBI Official Synonym Full Names: intercellular adhesion molecule 5
• NCBI Official Symbol: ICAM5
• NCBI Official Synonym Symbols: TLN; TLCN
• NCBI Protein Information: intercellular adhesion molecule 5
• UniProt Protein Name: Intercellular adhesion molecule 5
• UniProt Gene Name: ICAM5
• UniProt Synonym Gene Names: TLCN; TLN; ICAM-5
• UniProt Entry Name: ICAM5_HUMAN

NCBI Description

The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. [provided by RefSeq, Jul 2008]

Uniprot Description

ICAM5: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). Belongs to the immunoglobulin superfamily. ICAM family.

Protein type: Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: integrin binding; protein binding

Biological Process: cell-cell adhesion; cell adhesion; phagocytosis