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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human breast cancer tissue using PARP11 Polyclonal Antibody at dilution 1:30)

Rabbit PARP11 Polyclonal Antibody | anti-PARP11 antibody

PARP11 Polyclonal Antibody

Gene Names
PARP11; ARTD11; MIB006; C12orf6
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
PARP11; Polyclonal Antibody; PARP11 Polyclonal Antibody; ARTD11; MIB006; C12orf6; anti-PARP11 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
1.7mg/mL (varies by lot)
Sequence Length
232
Applicable Applications for anti-PARP11 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-1:200
Immunogen
Recombinant protein of human PARP11
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human breast cancer tissue using PARP11 Polyclonal Antibody at dilution 1:30)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human breast cancer tissue using PARP11 Polyclonal Antibody at dilution 1:30)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human lung cancer tissue using PARP11 Polyclonal Antibody at dilution 1:30)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human lung cancer tissue using PARP11 Polyclonal Antibody at dilution 1:30)
Related Product Information for anti-PARP11 antibody
Poly(ADP-ribosylation) is a method of DNA damage-dependent posttranslational modification that helps to rescue injured proliferating cells from cell death. The PARP (poly(ADP-ribose) polymerase) proteins comprise a superfamily of enzymes that functionally modify histones and other nuclear proteins, thereby preventing cell death. PARPs use NAD+ as a substrate to catalytically transfer ADP-ribose residues onto protein acceptors; a process that, when repeated multiple times, leads to the formation of poly(ADPribose) chains on the protein.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
39,597 Da
NCBI Official Full Name
PARP11 protein
NCBI Official Synonym Full Names
poly (ADP-ribose) polymerase family, member 11
NCBI Official Symbol
PARP11
NCBI Official Synonym Symbols
ARTD11; MIB006; C12orf6
NCBI Protein Information
poly [ADP-ribose] polymerase 11; poly [ADP-ribose] polymerase 11; ADP-ribosyltransferase diphtheria toxin-like 11
UniProt Protein Name
Poly [ADP-ribose] polymerase 11
UniProt Gene Name
PARP11
UniProt Synonym Gene Names
C12orf6; PARP-11; ARTD11
UniProt Entry Name
PAR11_HUMAN

Uniprot Description

PARP11: 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Transferase; EC 2.4.2.30

Chromosomal Location of Human Ortholog: 12p13.3

Molecular Function: NAD+ ADP-ribosyltransferase activity

Biological Process: metabolic process

Research Articles on PARP11

Similar Products

Product Notes

The PARP11 parp11 (Catalog #AAA2517969) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PARP11 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PARP11 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:50-1:200. Researchers should empirically determine the suitability of the PARP11 parp11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PARP11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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