Human Adiponectin Receptor 2 (ADIPOR2) RTU ELISA Kit | ADIPOR2 rtu elisa kit

Human Adiponectin Receptor 2 (ADIPOR2) ELISA Kit

Cat. Num. AAA457411

• Gene Names: ADIPOR2; PAQR2; ACDCR2
• Reactivity: Human
• Synonyms: Adiponectin Receptor 2 (ADIPOR2); Human Adiponectin Receptor 2 (ADIPOR2) ELISA Kit; PAQR2; ACDCR2; Progestin and AdipoQ Receptor Family Member II; ADIPOR2 rtu elisa kit

• Reactivity: Human
• Sequence Length: 386

• Assay Type: Sandwich
• Samples: Tissue Homogenates, Cell Lysates or Other Biological Fluids.
• Detection Range: 0.781-50ng/mL
• Sensitivity: 0.24ng/mL
• RTU ELISA Kit's Advantage: The Ready-To-Use (RTU) Kits require fewer steps in setup and take less time to run. Detection Solutions are pre-diluted and total incubation time is shorter than many other ELISA Kits.
• Preparation and Storage: For unopened kits: All the reagents should be kept at 4 degree C upon receipt.; For opened kits: Once the kit is opened, the remaining reagents still need to be stored according to the above storage conditions. In addition, return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for ADIPOR2 rtu elisa kit

Test Principle: The microtiter plate provided in this kit has been pre-coated with an antibody specific to ADIPOR2. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to ADIPOR2. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain ADIPOR2, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of ADIPOR2 in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 38261973
• NCBI GeneID: 79602
• NCBI Accession #: NP_078827.2
• NCBI GenBank Nucleotide #: NM_024551.2
• UniProt Accession #: Q86V24; Q53YY5; Q9H737
• Molecular Weight: 43,884 Da
• NCBI Official Full Name: adiponectin receptor protein 2
• NCBI Official Synonym Full Names: adiponectin receptor 2
• NCBI Official Symbol: ADIPOR2
• NCBI Official Synonym Symbols: PAQR2; ACDCR2
• NCBI Protein Information: adiponectin receptor protein 2
• UniProt Protein Name: Adiponectin receptor protein 2
• Protein Family: Adiponectin receptor protein
• UniProt Gene Name: ADIPOR2

NCBI Description

The adiponectin receptors, ADIPOR1 (MIM 607945) and ADIPOR2, serve as receptors for globular and full-length adiponectin (MIM 605441) and mediate increased AMPK (see MIM 602739) and PPAR-alpha (PPARA; MIM 170998) ligand activities, as well as fatty acid oxidation and glucose uptake by adiponectin (Yamauchi et al., 2003 [PubMed 12802337]).[supplied by OMIM, Mar 2008]

Uniprot Description

Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:12802337, PubMed:25855295). Required for normal body fat and glucose homeostasis. ADIPOQ-binding activates a signaling cascade that leads to increased PPARA activity, and ultimately to increased fatty acid oxidation and glucose uptake. Has intermediate affinity for globular and full-length adiponectin. Required for normal revascularization after chronic ischemia caused by severing of blood vessels ().