Human adiponectin receptor 2 ELISA Kit | ADIPOR2 elisa kit

Human Adiponectin Receptor Protein 2, ADIPOR2 ELISA Kit

Cat. Num. AAA2602879

• Gene Names: ADIPOR2; PAQR2; ACDCR2
• Reactivity: Human
• Synonyms: adiponectin receptor 2; Human Adiponectin Receptor Protein 2; ADIPOR2 ELISA Kit; ADIPOR2 elisa kit

• Reactivity: Human
• Specificity: No cross-reaction with other factors.

• Samples: Human serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant ADIPOR2 concentration
• Assay Type: Sandwich
• Detection Range: 10 ng/ml-0.156 ng/ml
• Sensitivity: 0.05 ng/ml.
• Intra-assay Precision: <= 8%
• Inter-assay Precision: <= 12%
• Preparation and Storage: Store all reagents at 2-8 degree C.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for ADIPOR2 elisa kit

Principle of the assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human ADIPOR2 monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.

NCBI and Uniprot Product Information

• NCBI GI #: 38261973
• NCBI GeneID: 79602
• NCBI Accession #: NP_078827.2
• NCBI GenBank Nucleotide #: NM_024551.2
• UniProt Accession #: Q86V24; Q53YY5; Q9H737
• Molecular Weight: 43,884 Da
• NCBI Official Full Name: adiponectin receptor protein 2
• NCBI Official Synonym Full Names: adiponectin receptor 2
• NCBI Official Symbol: ADIPOR2
• NCBI Official Synonym Symbols: PAQR2; ACDCR2
• NCBI Protein Information: adiponectin receptor protein 2; progestin and adipoQ receptor family member II
• UniProt Protein Name: Adiponectin receptor protein 2
• Protein Family: Adiponectin receptor protein
• UniProt Gene Name: ADIPOR2
• UniProt Synonym Gene Names: PAQR2
• UniProt Entry Name: ADR2_HUMAN

NCBI Description

The adiponectin receptors, ADIPOR1 (MIM 607945) and ADIPOR2, serve as receptors for globular and full-length adiponectin (MIM 605441) and mediate increased AMPK (see MIM 602739) and PPAR-alpha (PPARA; MIM 170998) ligand activities, as well as fatty acid oxidation and glucose uptake by adiponectin (Yamauchi et al., 2003 [PubMed 12802337]).[supplied by OMIM, Mar 2008]

Uniprot Description

ADIPOR2: Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some intermediate-affinity receptor activity for both globular and full-length adiponectin. Belongs to the ADIPOR family.

Protein type: Receptor, misc.; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 12p13.31

Cellular Component: plasma membrane; integral to membrane

Molecular Function: adiponectin binding; identical protein binding; hormone binding; protein heterodimerization activity; receptor activity

Biological Process: positive regulation of glucose import; hormone-mediated signaling; heart development; adiponectin-mediated signaling pathway; fatty acid oxidation; negative regulation of cell growth; female pregnancy; response to nutrient