Human A Disintegrin And Metalloprotease 22 (ADAM22) RTU ELISA Kit | ADAM22 rtu elisa kit

Human A Disintegrin And Metalloprotease 22 (ADAM22) ELISA Kit

Cat. Num. AAA457376

• Gene Names: ADAM22; MDC2; EIEE61; ADAM 22
• Reactivity: Human
• Synonyms: A Disintegrin And Metalloprotease 22 (ADAM22); Human A Disintegrin And Metalloprotease 22 (ADAM22) ELISA Kit; MDC2; Disintegrin And Metalloproteinase Domain-Containing Protein 22; Metalloproteinase-Like; Disintegrin-Like; And Cysteine-Rich Protein 2; ADAM22 rtu elisa kit

• Reactivity: Human
• Sequence Length: 859

• Assay Type: Sandwich
• Samples: Serum, Plasma, Tissue Homogenates or Other Biological Fluids.
• Detection Range: 0.156-10ng/mL
• Sensitivity: 0.057ng/mL
• RTU ELISA Kit's Advantage: The Ready-To-Use (RTU) Kits require fewer steps in setup and take less time to run. Detection Solutions are pre-diluted and total incubation time is shorter than many other ELISA Kits.
• Preparation and Storage: For unopened kits: All the reagents should be kept at 4 degree C upon receipt.; For opened kits: Once the kit is opened, the remaining reagents still need to be stored according to the above storage conditions. In addition, return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for ADAM22 rtu elisa kit

Test Principle: The microtiter plate provided in this kit has been pre-coated with an antibody specific to ADAM22. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to ADAM22. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain ADAM22, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of ADAM22 in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 4757722
• NCBI GeneID: 53616
• NCBI Accession #: NP_004185.1
• NCBI GenBank Nucleotide #: NM_004194.4
• UniProt Accession #: Q9P0K1; O75075; O75076; Q9P0K2; Q9UIA1; Q9UKK2
• Molecular Weight: 96,637 Da
• NCBI Official Full Name: disintegrin and metalloproteinase domain-containing protein 22 isoform 4
• NCBI Official Synonym Full Names: ADAM metallopeptidase domain 22
• NCBI Official Symbol: ADAM22
• NCBI Official Synonym Symbols: MDC2; EIEE61; ADAM 22
• NCBI Protein Information: disintegrin and metalloproteinase domain-containing protein 22
• UniProt Protein Name: Disintegrin and metalloproteinase domain-containing protein 22
• Protein Family: Disintegrin and metalloproteinase domain-containing protein
• UniProt Gene Name: ADAM22
• UniProt Synonym Gene Names: MDC2; ADAM 22

NCBI Description

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Unlike other members of the ADAM protein family, the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. In mice, it has been shown to be essential for correct myelination in the peripheral nervous system. Alternative splicing results in several transcript variants.[provided by RefSeq, Dec 2010]

Uniprot Description

Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein (PubMed:19692335). Involved in regulation of cell adhesion and spreading and in inhibition of cell proliferation. Neuronal receptor for LGI1.