Testing Data)
C-Reactive Protein (CRP) Protein | CRP protein
Human C-Reactive Protein (CRP)
Gene Names
crp.4-a; CRP; ptx1; crp.4a
Applications
SDS-Page
Purity
≥ 99 % by SDS-PAGE.
Synonyms
C-Reactive Protein (CRP); Human C-Reactive Protein (CRP); Human C-Reactive Protein (CRP).; CRP protein
Host
Human pleural fluid
Purity/Purification
≥ 99 % by SDS-PAGE.
Concentration
1 mg/ml. As determined by the Lowry method. (varies by lot)
Applicable Applications for CRP protein
SDS-PAGE
Preservative
50 mM Tris-HCl, 250 mM NaCl, 5 mM CaCl2, 0.1% NaN3, pH 8.0. Centrifuge before use!
Preparation and Storage
4°C for short-term storage and -20°C for long-term storage.
Testing Data)
Testing Data)
Related Product Information for CRP protein
Human C-reactive protein (CRP) is an acute phase protein produced by the liver. It is a member of the pentraxin family of proteins with five identical nonglycosylated subunits of 206 amino acids each (m.w. 24 kDa). Among other markers of inflammation, CRP has been showed the strongest association with cardiovascular events. Clinical studies demonstrated that coronary mortality among patients with unstable angina and elevated CRP is significantly higher comparing with the patients without elevated CRP. It is an important biomarker for detecting individuals at high risk of plaque rapture.
Product Categories/Family for CRP protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
C-reactive protein
NCBI Official Synonym Full Names
C-reactive protein, pentraxin-related, gene 4
NCBI Official Symbol
crp.4-a
NCBI Official Synonym Symbols
CRP; ptx1; crp.4a
NCBI Protein Information
C-reactive protein; C-reactive protein, pentraxin-related, gene 4 a
UniProt Protein Name
C-reactive protein
Protein Family
UniProt Gene Name
crp
UniProt Synonym Gene Names
CRP
UniProt Entry Name
CRP_XENLA
Uniprot Description
Function: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis, and complement fixation through its calcium-dependent binding to phosphorylcholine.
Cofactor: Binds 2 calcium ions per subunit
By similarity.
Subunit structure: Homodimer; disulfide-linked. It is not known if it assembles into a pentaxin (or pentraxin) structure. Pentaxins have a discoid arrangement of 5 non-covalently bound subunits.
Subcellular location: Secreted.
Developmental stage: Is initially detected at the late tail bud stage when the liver appears. Ref.1
Post-translational modification: Cys-89 or Cys-223 or Cys-236 could be involved in interchain disulfide linkage.
Sequence similarities: Belongs to the pentaxin family.Contains 1 pentaxin domain.
Similar Products
Product Notes
The CRP crp (Catalog #AAA390133) is a Protein produced from Human pleural fluid and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's C-Reactive Protein (CRP) can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the CRP crp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "C-Reactive Protein (CRP), Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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