Rabbit CRP (C-Reactive Protein) Antibody | anti-CRP antibody

Rabbit Anti-Human CRP (C-Reactive Protein) Affinity Pure

Cat. Num. AAA390098

• Gene Names: crp.4-a; CRP; ptx1; crp.4a
• Applications: ELISA, Immunoblot, Western Blot
• Synonyms: CRP (C-Reactive Protein); Rabbit Anti-Human CRP (C-Reactive Protein) Affinity Pure; Rabbit Anti-Human C-Reactive Protein (CRP); Polyclonal Antibody; Affinity Purified; anti-CRP antibody

• Host: Rabbit
• Specificity: Specifically binds to human CRP. Dilution for immunoblot and ELISA range: 200 to 160,000.
• Concentration: 1 mg / ml (OD 1.35 / 280 nm). (varies by lot)
• Sequence Length: 238

• Applicable Applications for anti-CRP antibody: ELISA (EIA), Immunoblot (IB)
• Application Notes: Dilution for Immunoblot & ELISA range: 1,000 to 160,000.; Use: The antibody can be used for detection of CRP in plasma and lipoproteins, immunoassays, immunoblots, enzyme conjugation, or biotinylation.
• Source Note: Polyclonal antibody purified by human CRP-Sepharose affinity column.*
• Preservative: 75 mM PBS, 75 mM NaCl, 0.02% NaN3, 0.5 mM EDTA, pH 7.2.
• Preparation and Storage: -20 degree C for long-term storage, 2-8 degree C for short-term storage. Aliquot to avoid repeated thaw and freeze.

Testing Data)

Related Product Information for anti-CRP antibody

Human C-reactive protein (CRP) is an acute phase protein produced by the liver. It is a member of the pentraxin family of proteins with five identical nonglycosylated subunits of 206 amino acids each (m.w. 24 kDa). Among other markers of inflammation, CRP has been showed the strongest association with cardiovascular events. Clinical studies demonstrated that coronary mortality among patients with unstable angina and elevated CRP is significantly higher comparing with the patients without elevated CRP. It is an important biomarker for detecting individuals at high risk of plaque rapture.

Product Categories/Family for anti-CRP antibody

Aff. Pure AB

NCBI and Uniprot Product Information

• NCBI GI #: 585008
• NCBI GeneID: 100337615
• UniProt Accession #: Q07203
• Molecular Weight: 27,085 Da
• NCBI Official Full Name: C-reactive protein
• NCBI Official Synonym Full Names: C-reactive protein, pentraxin-related, gene 4<
• NCBI Official Symbol: crp.4-a
• NCBI Official Synonym Symbols: CRP; ptx1; crp.4a
• NCBI Protein Information: C-reactive protein; C-reactive protein, pentraxin-related, gene 4 a
• UniProt Protein Name: C-reactive protein
• Protein Family: Cryparin
• UniProt Gene Name: crp
• UniProt Synonym Gene Names: CRP
• UniProt Entry Name: CRP_XENLA

Uniprot Description

Function: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis, and complement fixation through its calcium-dependent binding to phosphorylcholine.

Cofactor: Binds 2 calcium ions per subunit

By similarity.

Subunit structure: Homodimer; disulfide-linked. It is not known if it assembles into a pentaxin (or pentraxin) structure. Pentaxins have a discoid arrangement of 5 non-covalently bound subunits.

Subcellular location: Secreted.

Developmental stage: Is initially detected at the late tail bud stage when the liver appears. Ref.1

Post-translational modification: Cys-89 or Cys-223 or Cys-236 could be involved in interchain disulfide linkage.

Sequence similarities: Belongs to the pentaxin family.Contains 1 pentaxin domain.