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Testing Data (Peptide-+)

anti-Human, Mouse STEA2 Antibody | anti-STEA2 antibody

STEA2 Antibody

Gene Names
STEAP2; STMP; IPCA1; PUMPCn; STAMP1; PCANAP1
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Immunofluorescence, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
STEA2; STEA2 Antibody; EC 1.16.1.-; Six-transmembrane epithelial antigen of prostate 2; SixTransMembrane protein of prostate 1; Prostate cancer-associated protein 1; anti-STEA2 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse
Specificity
STEA2 antibody detects endogenous levels of total STEA2 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
490
Applicable Applications for anti-STEA2 antibody
Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes
IHC: 1:50-1:100
IF: 1:00-1:500
ELISA: 1:1000
Immunogen
The antiserum was produced against synthesized peptide derived from C-terminal of human STEA2.
Preparation and Storage
Store at-20 degree C for 1 year.

Testing Data

(Peptide-+)

Testing Data (Peptide-+)

Immunohistochemistry (IHC)

(Peptide-+ Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using STEA2 antibody. Immunofluorescence analysis of A549 cells, using STEA2 antibody.)

Immunohistochemistry (IHC) (Peptide-+ Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using STEA2 antibody. Immunofluorescence analysis of A549 cells, using STEA2 antibody.)
References
Korkmaz K.S., J. Biol. Chem. 277:36689-36696(2002). Porkka K.P., Lab. Invest. 82:1573-1582(2002). Ohgami R.S., Blood 108:1388-1394(2006).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
47,916 Da
NCBI Official Full Name
metalloreductase STEAP2 isoform a
NCBI Official Synonym Full Names
STEAP2 metalloreductase
NCBI Official Symbol
STEAP2
NCBI Official Synonym Symbols
STMP; IPCA1; PUMPCn; STAMP1; PCANAP1
NCBI Protein Information
metalloreductase STEAP2
UniProt Protein Name
Metalloreductase STEAP2
UniProt Gene Name
STEAP2
UniProt Synonym Gene Names
PCANAP1; STAMP1; PUMPCn

NCBI Description

This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Uniprot Description

Metalloreductase that has the ability to reduce both Fe3+ to Fe2+ and Cu2+ to Cu1+. Uses NAD+ as acceptor ().

Research Articles on STEA2

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Product Notes

The STEA2 steap2 (Catalog #AAA851260) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The STEA2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's STEA2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA). IHC: 1:50-1:100 IF: 1:00-1:500 ELISA: 1:1000. Researchers should empirically determine the suitability of the STEA2 steap2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STEA2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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