Testing Data
Rabbit STEAP2 Polyclonal Antibody | anti-STEAP2 antibody
Anti-STEAP2 Antibody
In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide
IHC: 1:50- 1:200
IF/IC: 1:50- 1:100
The antibody solution should be gently mixed before use.
Testing Data
Testing Data
The six-transmembrane epithelial antigen of prostate 2 (STEAP2) is a member of the STEAP family. The STEAP proteins are metalloreductases that has the ability to reduce both Fe3+ to Fe2+ and Cu2+ to Cu1+. Uses NAD+ as acceptor
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Uniprot Description
STEAP2: Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor. Belongs to the STEAP family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 1.16.1.-; Membrane protein, integral; Membrane protein, multi-pass; Oxidoreductase; Vesicle
Chromosomal Location of Human Ortholog: 7q21.13
Cellular Component: cytosol; early endosome; integral to Golgi membrane; integral to plasma membrane; plasma membrane; trans-Golgi network transport vesicle
Molecular Function: cupric reductase activity; transporter activity
Biological Process: copper ion import; endocytosis; Golgi to plasma membrane transport; regulated secretory pathway; response to hormone stimulus
Research Articles on STEAP2
Similar Products
Product Notes
The STEAP2 steap2 (Catalog #AAA846048) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-STEAP2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's STEAP2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB); Immunohistochemistry (IHC); Immunofluorescence (IF); Immunocytochemistry (ICC). WB: 1:500- 1:2000 IHC: 1:50- 1:200 IF/IC: 1:50- 1:100. Researchers should empirically determine the suitability of the STEAP2 steap2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STEAP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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