Typical Testing Data/Standard Curve
Human Trastuzumab (Herceptin) ELISA Kit
BioSim anti-Trastuzumab (Herceptin) (Human) ELISA Kit
Reactivity
Human
Synonyms
Trastuzumab (Herceptin); BioSim anti-Trastuzumab (Herceptin) (Human) ELISA Kit; Trastuzumab (Herceptin) elisa kit
Reactivity
Human
Application Notes
This ELISA kit is used for quantitative measurement of antibody against Trastuzumab in human serum and plasma
Samples
Serum and plasma
Detection Range
31 - 500 ng/ml
Sensitivity
30 ng/ml
Intra-assay Precision
Intra-Assay: CV < 15%
Inter-assay Precision
Inter-Assay: CV < 15% (CV (%) = SD/mean X 100)
Preparation and Storage
Store at 4 degree C
Typical Testing Data/Standard Curve
Typical Testing Data/Standard Curve
Related Product Information for Trastuzumab (Herceptin) elisa kit
Background/Introduction: Trastuzumab (Herclon®, Herceptin®) is a recombinant DNA-derived humanized monoclonal antibody that selectively targets the extracellular domain of the human epidermal growth factor receptor 2 protein (HER2). Trastuzumab has antitumor activity against HER2-positive human breast tumor cells in laboratory models and is active for the treatment of women with HER2-overexpressing breast cancers. In HER2 overexpressing cells, trastuzumab markedly down-regulates HER2 expression by accelerating receptor endocytosis and degradation and inhibits cell cycle progression by inducing the formation of p27Kip1/Cdk2 complexes. However, some patients develop unwanted immunogenicity, which leads to production of anti-drug-antibodies (ADAs) inactivating the therapeutic effects of the treatment and, in rare cases, inducing adverse effects. BioSimTM anti-Trastuzumab ELISA kit is designed to quantify/measure the antibody against Trastuzumab with high specificity and sensitivity in biological matrices.
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Product Notes
The Human Trastuzumab (Herceptin) (Catalog #AAA849159) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA849159 ELISA Kit recognizes Human Trastuzumab (Herceptin). This ELISA kit is used for quantitative measurement of antibody against Trastuzumab in human serum and plasma. Researchers should empirically determine the suitability of the Trastuzumab (Herceptin) for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Trastuzumab (Herceptin), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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