Typical Testing Data/Standard Curve (for reference only)
Human Avastin ELISA Kit
BioSim anti-Bevacizumab (Avastin) (Human) ELISA Kit
Reactivity
Human
Synonyms
Avastin; BioSim anti-Bevacizumab (Avastin) (Human) ELISA Kit; Avastin elisa kit
Reactivity
Human
Specificity
This kit is used for quantitative measurement of antibody against Bevacizumab
Assay Type
Sandwich
Samples
Human serum or plasma
Detection Range
62-500ng/ml
Sensitivity
30ng/ml
Precision
Intra-Assay: CV<15%
Inter-Assay: CV<15% (CV (%)= SD/mean X 100)
Inter-Assay: CV<15% (CV (%)= SD/mean X 100)
Recovery rate
85 - 115% with normal human serum samples with known concentrations
Cross Reactivity
Bevacizumab infusion camouflages/masks the presence of antibody to Bevacizumab (ATA) in serum/plasma samples. Therefore, blood sampling time is critical for detection of ATA.
Detection Method
Absorbance: 450nm
Features & Benefits
Easy, convenient, sensitive and time-saving method to measure the level of antibody against Bevacizumab in human serum and plasma. It is convenient to obtain blood sample just before the infusion of Bevacizumab or at least 2 weeks after the infusion of Bevacizumab.
Preparation and Storage
Store at 4 degree C
Shelf life: ~12 months
Shelf life: ~12 months
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Related Product Information for Avastin elisa kit
Bevacizumab (Avastin) is a recombinant human IgG1 monoclonal antibody specific for all human vascular endothelial growth factor-A (VEGF-A) isoforms. It has been demonstrated that bevacizumab, in combination with chemotherapy, resulted in increased survival in patients with previously untreated metastatic colorectal cancer relative to chemotherapy alone, leading to FDA approval of the first anti-angiogenic agent. However, some patients develop unwanted immunogenicity, which leads to production of anti-drug-antibodies (ADAs) inactivating the therapeutic effects of the treatment and, in rare cases, inducing adverse effects. BioSimTM anti-Bevacizumab ELISA kit is designed to quantify/measure the antibody against Bevacizumab with high specificity and sensitivity in biological matrices.
Product Categories/Family for Avastin elisa kit
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Product Notes
The Human Avastin (Catalog #AAA849162) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA849162 ELISA Kit recognizes Human Avastin. It is sometimes possible for the material contained within the vial of "Avastin, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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