Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Receptor-type tyrosine-protein phosphatase F (PTPRF) Standard Curve.)
Human Receptor-Type Tyrosine-Protein Phosphatase F (PTPRF) ELISA Kit | PTPRF elisa kit
Human Receptor-Type Tyrosine-Protein Phosphatase F (PTPRF) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Receptor-type tyrosine-protein phosphatase F (PTPRF) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Receptor-type tyrosine-protein phosphatase F (PTPRF) Standard Curve.)
Background: Receptor-type tyrosine-protein phosphatase F is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherens junctions, as well as in the control of beta-catenin signaling.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]
Uniprot Description
PTPRF: Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase). Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Receptor protein phosphatase, tyrosine; EC 3.1.3.48; Motility/polarity/chemotaxis; Membrane protein, integral
Chromosomal Location of Human Ortholog: 1p34
Cellular Component: integral to plasma membrane
Molecular Function: heparin binding; protein complex binding; transmembrane receptor protein tyrosine phosphatase activity; protein tyrosine phosphatase activity
Biological Process: cell migration; cell adhesion; transmembrane receptor protein tyrosine phosphatase signaling pathway
Disease: Breasts And/or Nipples, Aplasia Or Hypoplasia Of, 2
Research Articles on PTPRF
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Product Notes
The Human PTPRF ptprf (Catalog #AAA9714714) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9714714 ELISA Kit recognizes Human PTPRF. It is sometimes possible for the material contained within the vial of "Receptor-Type Tyrosine-Protein Phosphatase F (PTPRF), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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