Typical Testing Data/Standard Curve (for reference only)
Human Putative Potassium Channel Regulatory Protein (KCNRG) ELISA Kit | KCNRG elisa kit
Human Putative Potassium Channel Regulatory Protein (KCNRG) ELISA Kit
Gene Names
KCNRG; DLTET
Reactivity
Human
Synonyms
Putative Potassium Channel Regulatory Protein (KCNRG); Human Putative Potassium Channel Regulatory Protein (KCNRG) ELISA Kit; KCNRG; RP11-34F20.6; DLTET; KCNRG elisa kit
Reactivity
Human
Sequence Length
272
Assay Type
Sandwich
Preparation and Storage
Store at 2-8 degree C.
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Related Product Information for KCNRG elisa kit
Principle of the Assay: Human Putative Potassium Channel Regulatory Protein (KCNRG) ELISA Kit employs a two-site sandwich ELISA to quantitate KCNRG in samples. An antibody specific for KCNRG has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any KCNRG present is bound by the immobilized antibody. After removing any unbound substances, HRP-Conjugated Human KCNRG detection antibody is added to the wells. Following a wash to remove any unbound HRP reagent, a Chromogen solution is added to the wells and color develops in proportion to the amount of KCNRG bound in the initial step. The color development is stopped and the intensity of the color is measured.
Background/Introduction: KCNRG is a soluble protein with characteristics suggesting it forms hetero-tetramers with voltage-gated K+ channels and inhibits their function. KCNRG has been found to be predominatly expressed in lung tissue. Additionally, KCNRG transcripts are also found in liver and some other tissues, but in lower extent. Researchers at Uppsala University have found that KCNRG is found in the lower lung and constitutes an autoantigen in a rare disorder named autoimmune polyendocrine syndrome type 1 (APS1).
Background/Introduction: KCNRG is a soluble protein with characteristics suggesting it forms hetero-tetramers with voltage-gated K+ channels and inhibits their function. KCNRG has been found to be predominatly expressed in lung tissue. Additionally, KCNRG transcripts are also found in liver and some other tissues, but in lower extent. Researchers at Uppsala University have found that KCNRG is found in the lower lung and constitutes an autoantigen in a rare disorder named autoimmune polyendocrine syndrome type 1 (APS1).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
potassium channel regulatory protein isoform 1
NCBI Official Synonym Full Names
potassium channel regulator
NCBI Official Symbol
KCNRG
NCBI Official Synonym Symbols
DLTET
NCBI Protein Information
potassium channel regulatory protein
UniProt Protein Name
Potassium channel regulatory protein
Protein Family
UniProt Gene Name
KCNRG
UniProt Synonym Gene Names
CLLD4; Potassium channel regulator
NCBI Description
This gene encodes a protein which regulates the activity of voltage-gated potassium channels. This gene is on chromosome 13 and overlaps the gene for tripartite motif containing 13 on the same strand. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
Uniprot Description
KCNRG: Inhibits potassium fluxes in cells. May regulate Kv1 family channel proteins by retaining a fraction of channels in endomembranes. 3 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 13q14.2
Cellular Component: endoplasmic reticulum
Molecular Function: identical protein binding; protein binding
Biological Process: protein homooligomerization
Research Articles on KCNRG
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Product Notes
The Human KCNRG kcnrg (Catalog #AAA9715591) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9715591 ELISA Kit recognizes Human KCNRG. It is sometimes possible for the material contained within the vial of "Putative Potassium Channel Regulatory Protein (KCNRG), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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