Immunohistochemistry (IHC)
(KCNRG Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KCNRG Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Mouse KCNRG Polyclonal Antibody | anti-KCNRG antibody
KCNRG, CT (KCNRG, CLLD4, Potassium channel regulatory protein, Protein CLLD4) (APC)
Gene Names
TRIM13; CAR; LEU5; RFP2; DLEU5; RNF77
Reactivity
Mouse
Applications
Immunohistochemistry, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
KCNRG; Polyclonal Antibody; CT (KCNRG; CLLD4; Potassium channel regulatory protein; Protein CLLD4) (APC); Protein CLLD4; anti-KCNRG antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Sequence Length
407
Applicable Applications for anti-KCNRG antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes
IHC: 1:10-50
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Immunogen
KCNRG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 182-210 amino acids from the C-terminal region of human KCNRG.
Conjugate
APC
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Immunohistochemistry (IHC)
(KCNRG Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KCNRG Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(KCNRG Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KCNRG Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Western Blot (WB)
(KCNRG Antibody (C-term) western blot analysis in mouse liver,lung tissue lysates (35ug/lane).This demonstrates the KCNRG antibody detected the KCNRG protein (arrow).)
Western Blot (WB)
(KCNRG Antibody (C-term) western blot analysis in mouse liver,lung tissue lysates (35ug/lane).This demonstrates the KCNRG antibody detected the KCNRG protein (arrow).)
Related Product Information for anti-KCNRG antibody
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This gene is located on chromosome 13 within the minimal deletion region for B-cell chronic lymphocytic leukemia. Multiple alternatively spliced transcript variants have been found for this gene.
Product Categories/Family for anti-KCNRG antibody
References
Lerner, M., et al. Mol. Biol. Cell 18(5):1670-1682(2007). Skoblov, M., et al. Biochem. Biophys. Res. Commun. 342(3):859-866(2006). Corcoran, M.M., et al. Genes Chromosomes Cancer 40(4):285-297(2004). Dunham, A., et al. Nature 428(6982):522-528(2004). van Everdink, W.J., et al. Cancer Genet. Cytogenet. 146(1):48-57(2003).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
E3 ubiquitin-protein ligase TRIM13 isoform 1
NCBI Official Synonym Full Names
tripartite motif containing 13
NCBI Official Symbol
TRIM13
NCBI Official Synonym Symbols
CAR; LEU5; RFP2; DLEU5; RNF77
NCBI Protein Information
E3 ubiquitin-protein ligase TRIM13
UniProt Protein Name
Potassium channel regulatory protein
Protein Family
UniProt Gene Name
KCNRG
UniProt Synonym Gene Names
CLLD4; Potassium channel regulator
NCBI Description
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This gene is located on chromosome 13 within the minimal deletion region for B-cell chronic lymphocytic leukemia. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
KCNRG: Inhibits potassium fluxes in cells. May regulate Kv1 family channel proteins by retaining a fraction of channels in endomembranes. 3 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 13q14.2
Cellular Component: endoplasmic reticulum
Molecular Function: identical protein binding; protein binding
Biological Process: protein homooligomerization
Research Articles on KCNRG
Similar Products
Product Notes
The KCNRG kcnrg (Catalog #AAA6312732) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KCNRG, CT (KCNRG, CLLD4, Potassium channel regulatory protein, Protein CLLD4) (APC) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's KCNRG can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), FLISA, Western Blot (WB). IHC: 1:10-50 FLISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the KCNRG kcnrg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KCNRG, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
