Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Prostaglandin reductase 1 (PTGR1) Standard Curve.)
Human Prostaglandin Reductase 1 (PTGR1) ELISA Kit | PTGR1 elisa kit
Human Prostaglandin Reductase 1 (PTGR1) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Prostaglandin reductase 1 (PTGR1) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Prostaglandin reductase 1 (PTGR1) Standard Curve.)
Background: PTGR1 isan enzyme that is involved in the inactivation of the chemotactic factor, leukotriene B4. The encoded protein specifically catalyzes the NADP+ dependent conversion of leukotriene B4 to 12-oxo-leukotriene B4. A pseudogene of this gene is found on chromosome 1. Alternative splicing results in multiple transcript variants. Leukotriene B(4) 12-hydroxydehydrogenase catalyzes the conversion of leukotriene B(4) into 12-oxo-leukotriene B(4), its less-active metabolite.The identity between the porcine and human sequences they obtained is 83.5% at the amino acid level and 84.7% at the nucleotide level. Both enzymes are highly homologous with a protein, AdRab-F, expressed only in adult rabbit small intestine
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an enzyme that is involved in the inactivation of the chemotactic factor, leukotriene B4. The encoded protein specifically catalyzes the NADP+ dependent conversion of leukotriene B4 to 12-oxo-leukotriene B4. A pseudogene of this gene is found on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]
Uniprot Description
LTB4DH: Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Has no activity towards PGE1, PGE2 and PGE2-alpha. Catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4. Belongs to the NADP-dependent oxidoreductase L4BD family.
Protein type: Oxidoreductase; EC 1.3.1.74; EC 1.3.1.48
Chromosomal Location of Human Ortholog: 9q31.3
Cellular Component: cytoplasm
Molecular Function: 15-oxoprostaglandin 13-oxidase activity; zinc ion binding; 2-alkenal reductase activity
Biological Process: response to toxin; cyclooxygenase pathway; arachidonic acid metabolic process; leukotriene metabolic process
Research Articles on PTGR1
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Product Notes
The Human PTGR1 ptgr1 (Catalog #AAA9714733) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9714733 ELISA Kit recognizes Human PTGR1. It is sometimes possible for the material contained within the vial of "Prostaglandin Reductase 1 (PTGR1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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