Immunohistochemistry (IHC)
Rabbit PCP4 Polyclonal Antibody | anti-PCP4 antibody
Anti-PCP4 Antibody
Gene Names
PCP4; PEP-19
Reactivity
Rat, Mouse, Human
Applications
Immunohistochemistry, Western Blot
Purity
Affinity purification
Synonyms
PCP4; Polyclonal Antibody; Anti-PCP4 Antibody; Brain specific antigen PCP 4; Brain specific polypeptide PEP 19; Brain specific polypeptide PEP19; Brain-specific antigen PCP-4; Brain-specific polypeptide PEP-19; anti-PCP4 antibody
Host
Rabbit
Reactivity
Rat, Mouse, Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Polyclonal antibody to detect endogenous levels of PCP4 in human, mouse and rat samples
Purity/Purification
Affinity purification
Form/Format
Colorless liquid. In PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Concentration
1mg/mL (varies by lot)
Applicable Applications for anti-PCP4 antibody
Immunohistochemistry (IHC), Western Blot (WB)
Application Notes
IHC 1:100-1:300
WB: 1:500-1:2000
WB: 1:500-1:2000
Immunogen
Recombinant protein of human PCP4
Preparation and Storage
Store at -20 degree C
The antibody solution should be gently mixed before use.
Shelf life: ~12 months
The antibody solution should be gently mixed before use.
Shelf life: ~12 months
Immunohistochemistry (IHC)
Immunohistochemistry (IHC)
Related Product Information for anti-PCP4 antibody
PCP-4 (Purkinje cell protein 4), also known as PEP-19, is a calmodulin (CaM) regulatory protein that is highly expressed in neuronal cells. Through its IQ motif, PCP-4 mediates both the calcium-dependent binding properties of CaM and the rates of association and dissociation of calcium from the C-terminal domain of CaM. The IQ motif contains a serine residue which can be phosphorylated by all isoforms of protein kinase C (PKC). PCP-4 is implicated in uterine leiomyomas, as well as in neurodegenerative disorders such as Alzheimer's disease and Huntington's disease. Additionally, overexpression of PCP-4 is thought to play a role in cerebellar hypoplasia, a key feature of Down syndrome.
Product Categories/Family for anti-PCP4 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
6,791 Da
NCBI Official Full Name
Purkinje cell protein 4
NCBI Official Synonym Full Names
Purkinje cell protein 4
NCBI Official Symbol
PCP4
NCBI Official Synonym Symbols
PEP-19
NCBI Protein Information
Purkinje cell protein 4; brain-specific antigen PCP-4; brain specific polypeptide PEP19; brain-specific polypeptide PEP-19
UniProt Protein Name
Purkinje cell protein 4
Protein Family
UniProt Gene Name
PCP4
UniProt Synonym Gene Names
PEP19
UniProt Entry Name
PCP4_HUMAN
Uniprot Description
PCP4: Probable regulator of calmodulin signaling. Belongs to the PCP4 family.
Protein type: Calcium-binding; Cell development/differentiation
Chromosomal Location of Human Ortholog: 21q22.2
Cellular Component: cytosol; nucleus
Molecular Function: calmodulin binding
Biological Process: central nervous system development
Research Articles on PCP4
Similar Products
Product Notes
The PCP4 pcp4 (Catalog #AAA847556) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-PCP4 Antibody reacts with Rat, Mouse, Human and may cross-react with other species as described in the data sheet. AAA Biotech's PCP4 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB). IHC 1:100-1:300 WB: 1:500-1:2000. Researchers should empirically determine the suitability of the PCP4 pcp4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PCP4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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