Human MEK1 ELISA Kit | MEK1 elisa kit

MEK1 (Phospho) ELISA

Cat. Num. AAA494269

• Gene Names: MEK1; ATMEK1; F20B18.180; F20B18_180; MAP kinase/ ERK kinase 1; MEK1; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MKK1; NMAPKK
• Reactivity: Human
• Synonyms: MEK1; MEK1 (Phospho) ELISA; MEK1 elisa kit

• Reactivity: Human
• Sequence Length: 354

• Preparation and Storage: 2 - 8 degree C

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for MEK1 elisa kit

Background/Introduction: MCF-7 is a human breast cancer cell line that was first isolated in 1970 from the malignant adenocarcinoma breast tissue of a 69-year old woman. MCF-7 is the acronym of Michigan Cancer Foundation-7, referring to the institute in Detroit where the cell line was established. MCF-7 cells are useful for in vitro breast cancer studies because the cell line has retained several ideal characteristics particular to the mammary epithelium. These include the ability for MCF-7 cells to process estrogen via estrogen receptors. MCF-7 cells are also sensitive to cytokeratin. When grown in vitro, the cell line is capable of forming domes and the epithelial like cells grow in monolayers. Growth can also be inhibited using tumor necrosis factor alpha (TNF alpha). Our MCF-7/Luc cell line stably expresses firefly luciferase gene and Neomycin resistant gene.

Product Categories/Family for MEK1 elisa kit

Cytokines & Cell Signalling; Research Assays; Assay Categories

NCBI and Uniprot Product Information

• NCBI GI #: 2196704
• NCBI GeneID: 828713
• Molecular Weight: 34,087 Da
• NCBI Official Full Name: MEK1
• NCBI Official Symbol: MEK1
• NCBI Official Synonym Symbols: ATMEK1; F20B18.180; F20B18_180; MAP kinase/ ERK kinase 1; MEK1; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MKK1; NMAPKK
• NCBI Protein Information: mitogen-activated protein kinase kinase 1
• UniProt Protein Name: Mitogen-activated protein kinase kinase 1
• Protein Family: Meiosis-specific serine/threonine-protein kinase
• UniProt Gene Name: MKK1
• UniProt Synonym Gene Names: MEK1; AtMKK1; MAP kinase kinase 1
• UniProt Entry Name: M2K1_ARATH

NCBI Description

Member of MAP Kinase Kinase. Likely functions in a stress-activated MAPK pathway. Can phosphorylate the MAPK AtMPK4, in response to stress. Gets phosphorylated by MEKK1 in response to wounding.

Uniprot Description

MEKK1, MKK1/MKK2 and MPK4/MPK6 function in a signaling pathway that modulates the expression of genes responding to biotic and abiotic stresses and also plays an important role in pathogen defense by negatively regulating innate immunity. Activates by phosphorylation the downstream MPK4. Acts redundantly with MKK2. MKK1-MPK6 module mediates abscisic acid (ABA)-dependent CAT1 expression with H2O2 production and response to drought and salt stress. MKK1-MPK6 module is also involved in sugar signaling during the process of seed germination.