Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Leukocyte-associated immunoglobulin-like receptor 2 (LAIR2) Standard Curve.)
Human Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2) ELISA Kit | LAIR2 elisa kit
Human Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2) ELISA Kit
Gene Names
LAIR2; CD306
Reactivity
Human
Synonyms
Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2); Human Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2) ELISA Kit; LAIR2; XXbac-BCX535A19.6; CD306; MGC71634; leukocyte-associated Ig-like receptor 2; leukocyte-associated Ig-like receptor-2; LAIR2 elisa kit
Reactivity
Human
Specificity
Human Leukocyte-associated immunoglobulin-like receptor 2 (LAIR2) ELISA Kit has high sensitivity and excellent specificity for detection of Human LAIR2. No significant cross-reactivity or interference between Human LAIR2 and analogues was observed.
Sequence Length
152
Assay Type
Sandwich ELISA (Quantitative)
Samples
Cell Culture Supernatants, Serum, Plasma, Other Biological Fluids
Detection Method
Colorimetric
Usage Notes
* Do not mix components from different kit lots or use reagents beyond the kit expiration date.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Preparation and Storage
Store at 2-8 degree C.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Leukocyte-associated immunoglobulin-like receptor 2 (LAIR2) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Leukocyte-associated immunoglobulin-like receptor 2 (LAIR2) Standard Curve.)
Related Product Information for LAIR2 elisa kit
Description: This Human Leukocyte-associated immunoglobulin-like receptor 2 (LAIR2) ELISA Kit employs a two-site sandwich ELISA to quantitate LAIR2 in samples. An antibody specific for LAIR2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any LAIR2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for LAIR2 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of LAIR2 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Background: LAIR 2 is a member of the immunoglobulin superfamily. It was identified by its similarity to LAIR1, an inhibitory receptor present on mononuclear leukocytes. This gene maps to a region of 19q13.4, termed the leukocyte receptor cluster, which contains 29 genes in the immunoglobulin superfamily, including LAIR1. The function of this protein is unknown, although it is thought to be secreted and may help modulate mucosal tolerance. Two transcript variants encoding different isoforms have been found for this gene.By screening a human T-cell cDNA library,Meyaard et al. isolated a LAIR2 cDNA. The predicted LAIR2 protein contains 1 immunoglobulin-like domain, which is 84% homologous to that of LAIR1; it lacks both a transmembrane and a cytoplasmic domain, and therefore the authors suggested that it is secreted.
Background: LAIR 2 is a member of the immunoglobulin superfamily. It was identified by its similarity to LAIR1, an inhibitory receptor present on mononuclear leukocytes. This gene maps to a region of 19q13.4, termed the leukocyte receptor cluster, which contains 29 genes in the immunoglobulin superfamily, including LAIR1. The function of this protein is unknown, although it is thought to be secreted and may help modulate mucosal tolerance. Two transcript variants encoding different isoforms have been found for this gene.By screening a human T-cell cDNA library,Meyaard et al. isolated a LAIR2 cDNA. The predicted LAIR2 protein contains 1 immunoglobulin-like domain, which is 84% homologous to that of LAIR1; it lacks both a transmembrane and a cytoplasmic domain, and therefore the authors suggested that it is secreted.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
leukocyte-associated immunoglobulin-like receptor 2 isoform a
NCBI Official Synonym Full Names
leukocyte associated immunoglobulin like receptor 2
NCBI Official Symbol
LAIR2
NCBI Official Synonym Symbols
CD306
NCBI Protein Information
leukocyte-associated immunoglobulin-like receptor 2
UniProt Protein Name
Leukocyte-associated immunoglobulin-like receptor 2
Protein Family
UniProt Gene Name
LAIR2
UniProt Synonym Gene Names
CD306; LAIR-2
UniProt Entry Name
LAIR2_HUMAN
NCBI Description
The protein encoded by this gene is a member of the immunoglobulin superfamily. It was identified by its similarity to leukocyte-associated immunoglobulin-like receptor 1, a membrane-bound receptor that modulates innate immune response. The protein encoded by this locus is a soluble receptor that may play roles in both inhibition of collagen-induced platelet aggregation and vessel formation during placental implantation. This gene maps to a region of 19q13.4, termed the leukocyte receptor cluster, which contains 29 genes in the immunoglobulin superfamily. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2013]
Uniprot Description
LAIR-2: 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 19q13.4
Cellular Component: extracellular region
Research Articles on LAIR2
Similar Products
Product Notes
The Human LAIR2 lair2 (Catalog #AAA9715529) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9715529 ELISA Kit recognizes Human LAIR2. It is sometimes possible for the material contained within the vial of "Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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