Human Diacylglycerol Kinase iota (DGKI) ELISA Kit | DGKI elisa kit
Human Diacylglycerol Kinase iota (DGKI) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Background: DGKI is a member of the type IV diacylglycerol kinase subfamily. Diacylglycerol kinases regulate the intracellular concentration of diacylglycerol through its phosphorylation, producing phosphatidic acid. The specific role of the enzyme encoded by DGKI is undetermined, however, it may play a crucial role in the production of phosphatidic acid in the retina or in recessive forms of retinal degeneration.
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the type IV diacylglycerol kinase subfamily. Diacylglycerol kinases regulate the intracellular concentration of diacylglycerol through its phosphorylation, producing phosphatidic acid. The specific role of the enzyme encoded by this gene is undetermined, however, it may play a crucial role in the production of phosphatidic acid in the retina or in recessive forms of retinal degeneration. [provided by RefSeq, Jul 2008]
Uniprot Description
DGKI: a member of the type IV diacylglycerol kinase subfamily. Diacylglycerol kinases regulate the intracellular concentration of diacylglycerol through its phosphorylation, producing phosphatidic acid. The specific role of the enzyme encoded by undetermined, however, it may play a crucial role in the production of phosphatidic acid in the retina or in recessive forms of retinal degeneration. [provided by RefSeq, Jul 2008]
Protein type: Kinase, lipid; Motility/polarity/chemotaxis; EC 2.7.1.107; Lipid Metabolism - glycerophospholipid; Lipid Metabolism - glycerolipid
Chromosomal Location of Human Ortholog: 7q32.3-q33
Cellular Component: nucleoplasm; perinuclear region of cytoplasm; cytoplasm; plasma membrane; dendritic spine; synapse; nucleus
Molecular Function: protein binding; Ras GTPase binding; metal ion binding; diacylglycerol kinase activity; ATP binding; GTPase inhibitor activity; NAD+ kinase activity
Biological Process: platelet activation; protein kinase C activation; negative regulation of catalytic activity; positive regulation of Ras protein signal transduction; blood coagulation; phosphorylation
Research Articles on DGKI
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Product Notes
The Human DGKI dgki (Catalog #AAA9715742) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9715742 ELISA Kit recognizes Human DGKI. It is sometimes possible for the material contained within the vial of "Diacylglycerol Kinase iota (DGKI), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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