Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

JAGN1 blocking peptide

JAGN1 Peptide

Gene Names
JAGN1; SCN6; GL009
Applications
Blocking (BL)
Synonyms
JAGN1; JAGN1 Peptide; Jagunal homolog 1; JAGN1 blocking peptide
Ordering
For Research Use Only!
Host
Human
Form/Format
Liquid
Concentration
200 ug/mL (varies by lot)
Sequence Length
183
Applicable Applications for JAGN1 blocking peptide
Blocking (BL)
Buffer
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Location
19 amino acid peptide near the carboxy terminus of human JAGN1.
Preparation and Storage
Store at -20 degree C, stable for one year.
References
Boztug K, Jarvinen PM, Salzer E, et al. JAGN1 deficiency causes aberrant myeloid cell homeostasis and congenital neutropenia. Nat. Genet. 2014; 46:1021-7.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
21,125 Da
NCBI Official Full Name
protein jagunal homolog 1
NCBI Official Synonym Full Names
jagunal homolog 1
NCBI Official Symbol
JAGN1
NCBI Official Synonym Symbols
SCN6; GL009
NCBI Protein Information
protein jagunal homolog 1
UniProt Protein Name
Protein jagunal homolog 1
Protein Family
UniProt Gene Name
JAGN1
UniProt Entry Name
JAGN1_HUMAN

NCBI Description

The protein encoded by this gene is a transmembrane protein. It functions in the early secretory pathway and is necessary for neutrophil differentiation and survival. Mutations in this gene result in severe congenital neutropenia. [provided by RefSeq, Oct 2014]

Uniprot Description

JAGN1: May be required for endoplasmic reticulum organization. Belongs to the jagunal family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 3p25.2

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane

Molecular Function: protein binding

Biological Process: defense response to fungus; endoplasmic reticulum organization and biogenesis; exocytosis; neutrophil differentiation; neutrophil mediated immunity; protein transport; vesicle-mediated transport

Disease: Neutropenia, Severe Congenital, 6, Autosomal Recessive

Research Articles on JAGN1

Similar Products

Product Notes

The JAGN1 jagn1 (Catalog #AAA154431) is a Blocking Peptide produced from Human and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's JAGN1 can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). Researchers should empirically determine the suitability of the JAGN1 jagn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "JAGN1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.