SDS-Page
(SDS-PAGE 4-15% under reducing conditions and visualized by Coomassie blue staining showing a band at approx. 75 kDa)
Angiotensin-Converting Enzyme 2 (ACE2) Active Protein | ACE2 active protein
Recombinant Human Angiotensin-Converting Enzyme 2 (ACE2) Extracellular Domain
Purity
Affinity chromatography. Purity: >95% by SDS PAGE
Synonyms
Angiotensin-Converting Enzyme 2 (ACE2); Recombinant Human Angiotensin-Converting Enzyme 2 (ACE2) Extracellular Domain; ACE2 active protein
Host
HEK293 Cells
Purity/Purification
Affinity chromatography. Purity: >95% by SDS PAGE
Form/Format
Liquid ; PBS
Concentration
0.35 mg/ml (varies by lot)
Sequence
ECD Ser19-Asp615 with an immunoglobulin heavy chain variable signal peptide
Tag Information
HIS Tag C-Terminus
Extinction Coefficient
152220 M-1.cm-1 Abs 0.1% (=1 g/l) 2.171 assuming all pairs of Cys residues form cystines
Endotoxins
Negative on cell-based assay
Activity
Recognized by Recombinant Receptor Binding Domain of Spike protein in binding assay
Preparation and Storage
Store at -20 degree C. Avoid repeated freeze-thaw cycles Stable one week at 2 to 8 degree C after reconstitution under sterile conditions Stable 12 months -20 degree C to -80 degree C after reconstitution under sterile conditions
SDS-Page
(SDS-PAGE 4-15% under reducing conditions and visualized by Coomassie blue staining showing a band at approx. 75 kDa)
SDS-Page
(SDS-PAGE 4-15% under reducing conditions and visualized by Coomassie blue staining showing a band at approx. 75 kDa)
Western Blot (WB)
(Western Blot: ACE2-ECD HIS Tag detected with anti His Tag antibody)
Western Blot (WB)
(Western Blot: ACE2-ECD HIS Tag detected with anti His Tag antibody)
Related Product Information for ACE2 active protein
Angiotensin-Converting Enzyme 2, or ACE2, is a protein bound to the plasma membrane of lungs, arteries, heart, kidney, and intestines cells. ACE2 plays an important role in the renin-angiotensin-aldosterone system (RAAS), and a major physiological role in the regulation of the heart, kidney and blood pressure.
ACE2 is also the cellular receptor for severe acute respiratory syndrome – coronavirus (SARS-CoV)6 and the new coronavirus (SARS-CoV-2) that is causing the coronavirus disease 2019 (COVID-19) epidemic.
ACE2 is also the cellular receptor for severe acute respiratory syndrome – coronavirus (SARS-CoV)6 and the new coronavirus (SARS-CoV-2) that is causing the coronavirus disease 2019 (COVID-19) epidemic.
NCBI and Uniprot Product Information
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted Molecular Weight: 70.1 kDa; SDS Page: Approx. 75 kDa
Protein Family
Similar Products
Product Notes
The ACE2 (Catalog #AAA335829) is an Active Protein produced from HEK293 Cells and is intended for research purposes only. The product is available for immediate purchase. The tag for this protein is HIS Tag C-Terminus. The amino acid sequence is listed below: ECD Ser19-Asp6 15 with an immunoglob ulin heavy chain variable signal peptide. It is sometimes possible for the material contained within the vial of "Angiotensin-Converting Enzyme 2 (ACE2), Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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