Guinea Pig Phosphorylated Smad 2 (pSmad3) ELISA Kit | pSmad3 elisa kit
Guinea pig Phosphorylated Smad 2 (pSmad3) ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
PPPM1A: a Ser/Thr protein phosphatase of the PP2C family. Inhibits the activation of p38 and JNK kinase cascades induced by environmental stresses. Can also dephosphorylate cyclin-dependent kinases and may play a role in cell cycle control. Overexpression of this phosphatase activates the expression of p53, leading to G2/M cell cycle arrest and apoptosis.
Protein type: Protein phosphatase, Ser/Thr (non-receptor); Motility/polarity/chemotaxis; EC 3.1.3.16
Cellular Component: neuron projection; membrane; voltage-gated calcium channel complex; nucleus; cytosol
Molecular Function: protein C-terminus binding; signal transducer activity; protein binding; calmodulin-dependent protein phosphatase activity; manganese ion binding; magnesium ion binding; protein serine/threonine phosphatase activity; phosphoprotein phosphatase activity
Biological Process: positive regulation of protein export from nucleus; N-terminal protein myristoylation; Wnt receptor signaling pathway; positive regulation of I-kappaB kinase/NF-kappaB cascade; dephosphorylation; positive regulation of transcription, DNA-dependent; negative regulation of NF-kappaB import into nucleus; negative regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of transforming growth factor beta receptor signaling pathway; protein amino acid dephosphorylation; positive regulation of Wnt receptor signaling pathway; negative regulation of BMP signaling pathway
Research Articles on pSmad3
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Product Notes
The Guinea Pig pSmad3 ppm1a (Catalog #AAA2602196) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2602196 ELISA Kit recognizes Guinea Pig pSmad3. It is sometimes possible for the material contained within the vial of "Phosphorylated Smad 2 (pSmad3), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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