Guanine Nucleotide Binding Protein Recombinant Protein | GNAQ recombinant protein
Recombinant Human Guanine Nucleotide Binding Protein
Store frozen at -20°C for longer periods of time. For long term storage it is recommended to ass a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Description: GNAQ Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 382 amino acids (1-359 a.a) and having a molecular mass of 44.5kDa. GNAQ is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
NCBI and Uniprot Product Information
Uniprot Description
G-alpha(q): a guanine nucleotide-binding protein of the G12 class of G-alpha proteins. Agonist binding to Gq-coupled receptors may block Akt activation via the release of active G-alpha(q) subunits that inhibit phosphatidylinositol 3-kinase. Heterotrimeric G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.
Protein type: G protein; G protein, heterotrimeric; G protein, heterotrimeric alpha G(q)
Chromosomal Location of Human Ortholog: 9q21
Cellular Component: cytoplasm; lysosomal membrane; photoreceptor outer segment; plasma membrane
Molecular Function: GTPase activator activity; GTPase activity; protein binding; type 2A serotonin receptor binding
Biological Process: acetylcholine receptor signaling, muscarinic pathway; blood coagulation; dopamine receptor, phospholipase C activating pathway; entrainment of circadian clock; G-protein signaling, adenylate cyclase activating pathway; glutamate signaling pathway; negative regulation of protein kinase activity; phospholipase C activation; phototransduction, visible light; platelet activation; protein stabilization; regulation of action potential
Disease: Capillary Malformations, Congenital; Sturge-weber Syndrome
Similar Products
Product Notes
The GNAQ gnaq (Catalog #AAA141135) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSMTL ESIM ACCLSEEAKE ARRINDEIER QLRRDKRDAR RELKLLLLGT GESGKSTFIK QMRIIHGSGY SDEDKRGFTK LVYQNIFTAM QAMIRAMDTL KIPYKYEHNK AHAQLVREVD VEKVSAFENP YVDAIKSLWN DPGIQECYDR RREYQLSDST KYYLNDLDRV ADPAYLPTQQ DVLRVRVPTT GIIEYPFDLQ SVIFRMVDVG GQRSERRKWI HCFENVTSIM FLVALSEYDQ VLVESDNENR MEESKALFRT IITYPWFQNS SVILFLNKKD LLEEKIMYSH LVDYFPEYDG PQRDAQAARE FILKMFVDLN PDSDKIIYSH FTCATDTENI RFVFAAVKDT ILQLNLKEYN LV. It is sometimes possible for the material contained within the vial of "Guanine Nucleotide Binding Protein, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
