Testing Data
General Glutamate Carboxypeptidase II Assay Kit
PicoProbe Glutamate Carboxypeptidase II Activity Assay Kit
Reactivity
General
Synonyms
Glutamate Carboxypeptidase II; PicoProbe Glutamate Carboxypeptidase II Activity Assay Kit; folate hydrolase; GCPII; FOLH1; PSMA; prostate-specific membrane antigen; N-acetylated-alpha-linked acidic dipeptidase; NAALADase; Glutamate Carboxypeptidase II assay kit
Reactivity
General
Samples
Tissue Homogenates: Mouse Kidney, etc
Purified Enzyme or protein preparations
Purified Enzyme or protein preparations
Detection Method
Fluorometric: Ex/Em 535/587nm
Features & Benefits
Sensitive assay for measuring in various biological samples Glutamate Carboxypeptidase II (GCPII) Activity in Biological Samples/Preparations.
HTS adaptable
Simple procedure, Fast and convenient
HTS adaptable
Simple procedure, Fast and convenient
Preparation and Storage
Store at -20 degree C
Shelf life: ~12 months
Shelf life: ~12 months
Testing Data
Testing Data
Testing Data
Testing Data
Testing Data
Testing Data
Related Product Information for Glutamate Carboxypeptidase II assay kit
Glutamate Carboxypeptidase II [GCPII, EC 3.4.17.21; N-acetylated-alpha-linked acidic dipeptidase (NAALADase), prostate-specific membrane antigen (PSMA) or folate hydrolase (FOLH1) ] is a zinc-metallopeptidase, multifunctional protein. In humans, it is mainly expressed in the nervous system, prostate, small intestine and kidney. In males, PSMA is overexpressed in patients suffering prostate cancer and thus, it is used as a test marker for this disease. NAALADase, the brain isozyme, plays an important role in Glutamate biosynthesis and could be used for treating neuronal damage caused by excess glutamate in brain. PicoProbe Glutamate Carboxypeptidase II Activity Assay Kit is a simple plate-based fluorometric assay for the measurement of GCPII activity in Biological Samples. The provided substrate is transaminated in the presence of GCPII producing glutamate. The detection system is based on an enzymatic reaction in which a fluorogenic probe is reduced generating a stable signal. The reduced fluorophore produces a strong signal which is directly proportional to the amount of active GCPII in samples. The assay can detect as low as 0.5 uU of Glutamate Carboxypeptidase II.
Product Categories/Family for Glutamate Carboxypeptidase II assay kit
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Product Notes
The General Glutamate Carboxypeptidase II (Catalog #AAA849753) is an Assay Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA849753 Assay Kit recognizes General Glutamate Carboxypeptidase II. It is sometimes possible for the material contained within the vial of "Glutamate Carboxypeptidase II, Assay Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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