FABP6 recombinant protein

FABP6, isoform2, 1-128aa, Human, E Coli

Cat. Num. AAA203200

• Gene Names: FABP6; ILBP; I-15P; I-BAP; ILBP3; ILLBP; I-BABP; I-BALB
• Applications: SDS-Page
• Purity: > 95% by SDS-PAGE
• Synonyms: FABP6; isoform2; 1-128aa; Human; E Coli; Fatty acid binding protein 6; I-BABP; I-15P; ILLBP; ILBP; ILBP3; I-BAP; I-BALB; Gastrotropin; Fatty acid binding protein 6 Fatty acid binding protein 6; ileal (gastrotropin); GT; I 15P; I BABP; I BALB; I BAP; I15P; IBABP; IBALB; IBAP; Ileal lipid binding protein; Intestinal 15 kDa protein; Intestinal bile acid binding protein.; FABP6 recombinant protein

• Host: E Coli
• Purity/Purification: > 95% by SDS-PAGE
• Form/Format: Liquid in phosphate buffered saline (pH 7.4), 10% glycerol
• Concentration: 1 mg/ml (determined by Bradford assay) (varies by lot)
• Sequence: MAFTGKFEME SEKNYDEFMK LLGISSDVIE KAHNFKIVTE VQQDGQDFTW SQHYYGGHTM TNKFTVGKES NIQTMGGKTF KATVQMEGGK LVVNFPNYHQ TSEIVGDKLV EVSTIGGVTY ERVSKRLA
• Sequence Length: 128

• Applicable Applications for FABP6 recombinant protein: SDS-PAGE
• Antigen Species: Human
• Preparation and Storage: Can be stored at 4 degree C short term (1-2 weeks).; For long term storage, aliquot and store at -20 degree C or -70 degree C.; Avoid repeated freezing and thawing cycles.

SDS-Page

Related Product Information for FABP6 recombinant protein

FABP-6 is a cytosolic protein that binds bile acids with a high affinity. In the small intestine, its expression is restricted to the ileum where it is involved in the enterohepatic circulation of bile acids. Alternate transcription promoters generate two transcript variants, encoding a 128 aa and a 177 aa residue protein. Human FABP6 isoform 2 contains 128 amino acid residues and is believed to be acetylated on Ala2. It binds both fatty acids and bile acids and has roles in fatty acid transport and metabolism. Recombinant human FABP-6 was expressed in E Coli and purified by using conventional chromatography techniques.

Product Categories/Family for FABP6 recombinant protein

Cell Cycle

References

Ohmachi T., et al. (2006). Clin Cancer Res. Sep 1; 12 (17):5090-5.; Grober J., et al. (1999) J Biol Chem. Oct 15; 274 (42):29749-54.;

NCBI and Uniprot Product Information

• NCBI GI #: 18490679
• NCBI GeneID: 2172
• Molecular Weight: 14kDa (128aa), confirmed by MALDI-TOF.
• NCBI Official Full Name: FABP6 protein
• NCBI Official Synonym Full Names: fatty acid binding protein 6
• NCBI Official Symbol: FABP6
• NCBI Official Synonym Symbols: ILBP; I-15P; I-BAP; ILBP3; ILLBP; I-BABP; I-BALB
• NCBI Protein Information: gastrotropin
• UniProt Protein Name: Gastrotropin
• Protein Family: Gastrotropin
• UniProt Gene Name: FABP6
• UniProt Synonym Gene Names: ILBP; ILLBP; GT; ILBP; I-15P; I-BABP

NCBI Description

This gene encodes the ileal fatty acid binding protein. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP6 and FABP1 (the liver fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. Transcript variants generated by alternate transcription promoters and/or alternate splicing have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

Binds to bile acids and is involved in enterohepatic bile acid metabolism. Required for efficient apical to basolateral transport of conjugated bile acids in ileal enterocytes (). In vitro binds to bile acids in the order: deoxycholic acid > cholic acid > chenodeoxycholic acid and respective BA conjugation modifies affinities in the order taurine-conjugated > glycine-conjugated > unconjugated bile acids. Stimulates gastric acid and pepsinogen secretion ().